Faculty of Health Sciences, Adelaide Dental School, The University of Adelaide, Adelaide, South Australia, Australia.
Periodontol 2000. 2018 Oct;78(1):7-11. doi: 10.1111/prd.12237.
Personalized medicine is a medical model that involves the tailoring of healthcare - with medical decisions, practices, and/or products being customized to an individual patient. In this model, diagnostic testing is often employed for selecting appropriate and optimal therapies based on the context of a patient's genetic content or other epidemiologic, sociologic, molecular, physiologic, or cellular analyses. With the advent of major advances in periodontal medicine, including genomic discoveries and greater understanding of the multifactorial nature of periodontitis, it seems that the time is ripe to use personalized medicine as a model for personalized periodontics. This volume of Periodontology 2000 explores how new advances in our understanding of periodontitis within a medical model can evolve into new treatment strategies tailor-made for individual patients and not merely based on wholesale treatment paradigms.
个性化医疗是一种医疗模式,涉及医疗保健的定制化——医疗决策、实践和/或产品根据患者的个体遗传信息或其他流行病学、社会学、分子、生理学或细胞分析进行定制。随着牙周医学的重大进展,包括基因组发现和对牙周炎多因素性质的更深入了解,似乎是时候将个性化医疗作为个性化牙周病学的模型了。《牙周病学 2000 年》的这一卷探讨了在医学模型中对牙周炎的理解的新进展如何演变成针对个体患者的新治疗策略,而不仅仅是基于整体治疗模式。