Hermanek P
Hepatogastroenterology. 1986 Aug;33(4):180-3.
Among the gastric cancers, the percentage of diffuse carcinomas decreases with increasing age, while the incidence of the intestinal type increases markedly (up to 50 years 29.6%, older than 70 years 61.5%). Accordingly, in patients older than 70, gastric carcinomas limited to the antrum are seen significantly more frequently (32.5%) than in younger patients (21.1%). In patients aged 70 years or less, the rectum is more frequently affected than the colon (ratio 1.41:1), than is the case in older patients (1.17:1). With respect to stage distribution and the pTNM classification, colorectal carcinomas and gastric carcinomas show only small age-related differences. The prognosis of both carcinomas is independent of age when the survival rates are corrected for age, post-operative mortality is excluded, and only patients with identical stages are compared. In patients older than 70, cancer is not less aggressive, but, as a result of the limitations of therapeutic possibilities, and greater side effects of treatment, is more dangerous than in younger patients.
在胃癌中，弥漫性癌的比例随年龄增长而下降，而肠型癌的发病率则显著上升（50岁以下为29.6%，70岁以上为61.5%）。因此，在70岁以上的患者中，局限于胃窦的胃癌明显比年轻患者更常见（32.5%对21.1%）。在70岁及以下的患者中，直肠比结肠更易受累（比例为1.41:1），而在老年患者中则为（1.17:1）。关于分期分布和pTNM分类，结直肠癌和胃癌仅显示出与年龄相关的微小差异。当校正年龄生存率、排除术后死亡率且仅比较相同分期的患者时，这两种癌症的预后与年龄无关。在70岁以上的患者中，癌症并非侵袭性较小，但由于治疗可能性的限制以及治疗的副作用更大，比年轻患者更危险。
