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大肠杆菌dnaA基因产物对质粒F维持的需求。

Requirement of the Escherichia coli dnaA gene product for plasmid F maintenance.

作者信息

Kline B C, Kogoma T, Tam J E, Shields M S

出版信息

J Bacteriol. 1986 Oct;168(1):440-3. doi: 10.1128/jb.168.1.440-443.1986.

DOI:10.1128/jb.168.1.440-443.1986
PMID:3020005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC213474/
Abstract

There are DnaA protein-binding sites in at least one F origin of replication, and only potentially leaky dnaA(Ts) mutations had ever been used in previous studies indicating that F replication was independent of the dnaA gene product. Here we show that an Escherichia coli dnaA::Tn10 host which does not make a dnaA gene product cannot sustain autonomous or integrated F plasmid maintenance.

摘要

在至少一个F复制起点存在DnaA蛋白结合位点，并且在先前表明F复制独立于dnaA基因产物的研究中，仅使用了潜在渗漏的dnaA（Ts）突变。在这里我们表明，不产生dnaA基因产物的大肠杆菌dnaA::Tn10宿主不能维持自主或整合的F质粒的维持。

相似文献

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Requirement of the Escherichia coli dnaA gene product for plasmid F maintenance.大肠杆菌dnaA基因产物对质粒F维持的需求。
J Bacteriol. 1986 Oct;168(1):440-3. doi: 10.1128/jb.168.1.440-443.1986.
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本文引用的文献

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Transduction of linked genetic characters of the host by bacteriophage P1.噬菌体P1对宿主连锁遗传性状的转导
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Replication and incompatibility of F and plasmids in the IncFI Group.F质粒及IncFI组中质粒的复制与不相容性
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Control of plasmid R1 replication: functions involved in replication, copy number control, incompatibility, and switch-off of replication.质粒R1复制的控制：涉及复制、拷贝数控制、不相容性及复制关闭的功能
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Separation of the minimal replication region of the F plasmid into a replication origin segment and a trans-acting segment.F质粒最小复制区域分离为复制起始片段和反式作用片段。
Mol Gen Genet. 1982;186(3):372-7. doi: 10.1007/BF00729456.
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P1 plasmid replication: replicon structure.P1质粒复制：复制子结构
J Mol Biol. 1984 Mar 5;173(3):307-24. doi: 10.1016/0022-2836(84)90123-2.
6
Identification of the minimal essential region for the replication origin of miniF plasmid.微小F质粒复制起点最小必需区域的鉴定
Mol Gen Genet. 1984;196(2):373-8. doi: 10.1007/BF00328075.
7
Primary structure of the essential replicon of the plasmid pSC101.质粒pSC101必需复制子的一级结构。
Proc Natl Acad Sci U S A. 1983 Nov;80(21):6557-61. doi: 10.1073/pnas.80.21.6557.
8
Lambda placMu: a transposable derivative of bacteriophage lambda for creating lacZ protein fusions in a single step.λplacMu：一种噬菌体λ的可转座衍生物，用于一步构建lacZ蛋白融合体。
J Bacteriol. 1984 Jun;158(3):1084-93. doi: 10.1128/jb.158.3.1084-1093.1984.
9
RNase H confers specificity in the dnaA-dependent initiation of replication at the unique origin of the Escherichia coli chromosome in vivo and in vitro.核糖核酸酶H在体内和体外对大肠杆菌染色体独特起始点处依赖于dnaA的复制起始过程赋予特异性。
Proc Natl Acad Sci U S A. 1984 Feb;81(4):1040-4. doi: 10.1073/pnas.81.4.1040.
10
Purified dnaA protein in initiation of replication at the Escherichia coli chromosomal origin of replication.纯化的DnaA蛋白在大肠杆菌染色体复制起点处启动复制过程中的作用。
Proc Natl Acad Sci U S A. 1983 Oct;80(19):5817-21. doi: 10.1073/pnas.80.19.5817.