Berlyn M K
Department of Biology and School of Forestry and Environmental Studies, Yale University, New Haven, Connecticut 06520-8104, USA.
Microbiol Mol Biol Rev. 1998 Sep;62(3):814-984. doi: 10.1128/MMBR.62.3.814-984.1998.
This map is an update of the edition 9 map by Berlyn et al. (M. K. B. Berlyn, K. B. Low, and K. E. Rudd, p. 1715-1902, in F. C. Neidhardt et al., ed., Escherichia coli and Salmonella: cellular and molecular biology, 2nd ed., vol. 2, 1996). It uses coordinates established by the completed sequence, expressed as 100 minutes for the entire circular map, and adds new genes discovered and established since 1996 and eliminates those shown to correspond to other known genes. The latter are included as synonyms. An alphabetical list of genes showing map location, synonyms, the protein or RNA product of the gene, phenotypes of mutants, and reference citations is provided. In addition to genes known to correspond to gene sequences, other genes, often older, that are described by phenotype and older mapping techniques and that have not been correlated with sequences are included.
此图谱是对Berlyn等人绘制的第9版图谱的更新(M. K. B. Berlyn、K. B. Low和K. E. Rudd,第1715 - 1902页,载于F. C. Neidhardt等人编著的《大肠杆菌与沙门氏菌:细胞与分子生物学》第2版,第2卷,1996年)。它采用了由完整序列确定的坐标,整个环状图谱表示为100分钟,并添加了1996年以来发现和确定的新基因,剔除了那些已证明与其他已知基因相对应的基因。后者作为同义词包含在内。提供了一份按字母顺序排列的基因列表,列出了图谱位置、同义词、基因的蛋白质或RNA产物、突变体的表型以及参考文献。除了已知与基因序列相对应的基因外,还包括其他通常较古老的基因,这些基因通过表型和较古老的图谱绘制技术进行描述,并且尚未与序列相关联。