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[药用植物中硒多糖的最新研究进展]

[Recent research progress of selenium polysaccharides from medicinal plants].

作者信息

Liang Huan, Huang Jin, Wang Li, Chen Ji, Tian Meng-Liang

机构信息

College of Agronomy, Sichuan Agricultural University, Chengdu 611130, China.

Institute for New Rural Development, Sichuan Agricultural University, Chengdu 611130, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2018 Aug;43(15):3080-3092. doi: 10.19540/j.cnki.cjcmm.20180426.002.

Abstract

Selenium polysaccharides (Se polysaccharides) are a kind of organic selenium compounds which obtain the activities from Se and polysaccharides. Comparing to Se or polysaccharides, Se polysaccharides exhibit improved biological activities and are more prone to be absorbed by human bodies, therefore, they have been widely used in medical applications, such as immunomodulation, anti-tumor, anti-oxidation, anti-aging. Due to their unique pharmacological activities, Se polysaccharides from medicinal plants have gradually become a research hotspot. However, only a few of Se polysaccharides have been separated and purified in recent years. The structure of polysaccharides is also very complex, therefore, determination of the chemical structure and mechanism of bioactivity of Se polysaccharide in vivo remain to be further studied. This article systematically introduced the main source and biological activities of Se polysaccharides from medicinal plants. The purpose of this review is to provide a basis for the further research of Se polysaccharides.

摘要

硒多糖是一类有机硒化合物,兼具硒和多糖的活性。与硒或多糖相比,硒多糖具有更好的生物活性,更易于被人体吸收,因此,它们已广泛应用于医学领域,如免疫调节、抗肿瘤、抗氧化、抗衰老等。由于其独特的药理活性,药用植物中的硒多糖逐渐成为研究热点。然而,近年来仅分离纯化出少数几种硒多糖。多糖的结构也非常复杂,因此,硒多糖的化学结构及其体内生物活性机制的确定仍有待进一步研究。本文系统介绍了药用植物中硒多糖的主要来源和生物活性。本综述的目的是为硒多糖的进一步研究提供依据。

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