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支气管肺发育不良:病理生理学和潜在的抗炎治疗。

Bronchopulmonary dysplasia: Pathophysiology and potential anti-inflammatory therapies.

机构信息

The Ritchie Centre, Hudson Institute of Medical Research, Department of Obstetrics and Gynecology, Monash University, Clayton, VIC 3168, Australia; Human Sciences and Centre for Neonatal Research and Education, The University of Western Australia, Crawley, WA, Australia.

Human Sciences and Centre for Neonatal Research and Education, The University of Western Australia, Crawley, WA, Australia.

出版信息

Paediatr Respir Rev. 2019 Apr;30:34-41. doi: 10.1016/j.prrv.2018.07.007. Epub 2018 Jul 29.

Abstract

Inflammation of the preterm lungs is key to the pathogenesis of bronchopulmonary dysplasia (BPD), whether it arises as a consequence of intrauterine inflammation or postnatal respiratory management. This review explores steroidal and non-steroidal therapies for reducing neonatal pulmonary inflammation, aimed at treating or preventing BPD.

摘要

早产儿肺部炎症是支气管肺发育不良(BPD)发病机制的关键,无论是由宫内炎症还是产后呼吸管理引起的。本综述探讨了用于减轻新生儿肺部炎症的甾体和非甾体治疗方法,旨在治疗或预防 BPD。

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