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可能影响驾驶员的药物:预防伤害的风险与策略

Potentially Driver-Impairing Medications: Risks and Strategies for Injury Prevention.

作者信息

Ivers Timothy, White Nicole D

机构信息

Creighton University School of Pharmacy and Health Professions, Omaha, Nebraska.

出版信息

Am J Lifestyle Med. 2016 Jan 13;10(1):17-20. doi: 10.1177/1559827615609050. eCollection 2016 Jan-Feb.

DOI:10.1177/1559827615609050
PMID:30202255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6124861/
Abstract

Impaired driving is a major cause of motor vehicle accidents, injury, and fatality. Several classes of medication have been found to affect a driver's cognition, judgment, and reaction time and may put patients at increased risk for accidents and injury. This article will explore medications with side effects posing a potential threat to drivers, including anxiolytics, sedative hypnotics, antihistamines, and antidepressants, as well as describe potential strategies for mitigating or minimizing such risks.

摘要

酒后驾车是机动车事故、受伤和死亡的主要原因。已发现几类药物会影响驾驶员的认知、判断力和反应时间,并可能使患者面临更高的事故和受伤风险。本文将探讨其副作用对驾驶员构成潜在威胁的药物,包括抗焦虑药、镇静催眠药、抗组胺药和抗抑郁药,并描述减轻或最小化此类风险的潜在策略。

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本文引用的文献

1
Sedative Hypnotic Medication Use and the Risk of Motor Vehicle Crash.镇静催眠药物的使用与机动车碰撞风险
Am J Public Health. 2015 Aug;105(8):e64-9. doi: 10.2105/AJPH.2015.302723. Epub 2015 Jun 11.
2
Middle-of-the-night administration of sleep medication: a critical review of the effects on next morning driving ability.夜间服用助眠药物:对次日早晨驾驶能力影响的批判性综述。
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Effects of benzodiazepines, antidepressants and opioids on driving: a systematic review and meta-analysis of epidemiological and experimental evidence.苯二氮䓬类药物、抗抑郁药和阿片类药物对驾驶的影响:流行病学和实验证据的系统评价和荟萃分析。
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4
The relationship between benzodiazepine use and traffic accidents: A systematic literature review.苯二氮䓬类药物使用与交通事故的关系:系统文献回顾。
CNS Drugs. 2010 Aug;24(8):639-53. doi: 10.2165/11533170-000000000-00000.
5
The impact of benzodiazepines on safe driving.苯二氮䓬类药物对安全驾驶的影响。
Traffic Inj Prev. 2008 Oct;9(5):404-13. doi: 10.1080/15389580802161943.
6
Driving under the influence of drugs in Sweden with zero concentration limits in blood for controlled substances.在瑞典,若受药物影响驾车,对于管制药品血液中浓度限制为零。
Traffic Inj Prev. 2005 Dec;6(4):317-22. doi: 10.1080/15389580500253760.
7
Antihistamines and driving ability: evidence from on-the-road driving studies during normal traffic.抗组胺药与驾驶能力:来自正常交通情况下道路驾驶研究的证据。
Ann Allergy Asthma Immunol. 2004 Mar;92(3):294-303; quiz 303-5, 355. doi: 10.1016/S1081-1206(10)61566-9.
8
Antidepressants and driver impairment: empirical evidence from a standard on-the-road test.抗抑郁药与驾驶能力受损:来自标准道路测试的实证证据。
J Clin Psychiatry. 2003 Jan;64(1):20-9.
9
Association of road-traffic accidents with benzodiazepine use.道路交通事故与苯二氮䓬类药物使用的关联。
Lancet. 1998 Oct 24;352(9137):1331-6. doi: 10.1016/s0140-6736(98)04087-2.
10
Venlafaxine's effects on healthy volunteers' driving, psychomotor, and vigilance performance during 15-day fixed and incremental dosing regimens.文拉法辛在15天固定剂量和递增剂量给药方案期间对健康志愿者驾驶、精神运动及警觉表现的影响。
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