Wang Jianlong, Yang Cun
Pediatric Intensive Care Unit, Jining No.1, Pepole's Hospital, Jining, China.
Pak J Pharm Sci. 2018 Jul;31(4(Special)):1649-1652.
In the present study, the clinical effect of Sequential Therapy with Azithromycin in children mycoplasma pneumoniae pneumonia is observed and analyzed. The 160 children who were diagnosed as mycoplasma pneumoniae pneumonia were selected as subjects. They were randomly divided into two groups: study group and reference group and each group with 80 cases. Among them, the children in study group were carried out sequential therapy of erythromycin and the sequential therapy of azithromycin in reference group. The overall treatment efficiency, the incidence of adverse reactions, the time of symptom recovery and hospitalization were compared between the two groups. Through comparing the efficiency of overall treatment between two groups, the study group has more significant advantages than reference group: P<0.05; through comparing the time of symptoms recovery and hospitalization, study group is significantly less than reference group: P<0.05; in addition, through comparing the incidence of adverse reactions, the difference between two groups is not obvious: P>0.05. For sequential therapy of azithromycin in children mycoplasma pneumoniae pneumonia, it can achieve good therapeutic effect and has no serious adverse reactions, which has tremendous applied values.
本研究对阿奇霉素序贯疗法治疗儿童支原体肺炎的临床效果进行观察与分析。选取160例确诊为支原体肺炎的儿童作为研究对象，随机分为两组：研究组和参照组，每组80例。其中，研究组患儿采用红霉素序贯疗法，参照组患儿采用阿奇霉素序贯疗法。比较两组的总体治疗有效率、不良反应发生率、症状恢复时间及住院时间。通过比较两组的总体治疗有效率，研究组比参照组具有更显著优势：P<0.05；通过比较症状恢复时间及住院时间，研究组明显短于参照组：P<0.05；此外，通过比较不良反应发生率，两组差异不明显：P>0.05。对于儿童支原体肺炎采用阿奇霉素序贯疗法，可取得良好治疗效果且无严重不良反应，具有巨大的应用价值。
