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慢性肾功能衰竭伴异常子宫出血患者的腹腔镜子宫切除术

Laparoscopic hysterectomy in chronic renal failure patients with abnormal uterine bleeding.

作者信息

Zhao Shan, Yan Li, Zhao Zhiyi, Hou Ming, Rong Fengnian

机构信息

a Department of Gynecology , Qianfoshan Hospital Affiliated to Shandong University , Jinan , China.

b Department of Anesthesiology , Qianfoshan Hospital Affiliated to Shandong University , Jinan , China.

出版信息

Minim Invasive Ther Allied Technol. 2019 Feb;28(1):41-45. doi: 10.1080/13645706.2018.1467459. Epub 2018 Sep 11.

Abstract

BACKGROUND

Chronic renal failure (CRF) in women is frequently accompanied by endocrine disturbances leading to abnormal uterine bleeding (AUB). Recurrence of AUB is the most significant problem following current treatment approaches. Laparoscopic hysterectomy (LH) might be taken into consideration for patients who no longer want to preserve their fertility; however, these patients are in high-risk groups for minimally invasive surgery. Our goal was to determine whether LH is a good option for the treatment of AUB in patients with CRF when the associated risks are carefully managed.

MATERIAL AND METHODS

This study included five patients who underwent LH for abnormal uterine bleeding between 2013 and 2016. Enhanced perioperative management and techniques were adopted to allow LH with minimized risks to the patient.

RESULTS

All patients underwent LH successfully, without organ failure, heavy infection or abdominal cavity bleeding during the perioperative period. Operation times ranged from 95 to 152 min (mean time 117.6 min). The mean intraoperative blood loss was 24 ml. No recurrence was observed during the 18 months follow-up period.

CONCLUSION

For CRF patients with AUB who no longer want to preserve their fertility, hysterectomy may be a better option, not only to permanently resolve the problem, but also to remove the risk of future uterine lesions. The improved protocols minimized the specific risks of laparoscopy arising from the patient's coexisting medical problems, making LH a feasible treatment approach in CRF patients with AUB.

摘要

背景

女性慢性肾衰竭(CRF)常伴有内分泌紊乱,导致异常子宫出血(AUB)。AUB复发是当前治疗方法后最显著的问题。对于不再希望保留生育能力的患者,可考虑腹腔镜子宫切除术(LH);然而,这些患者属于微创手术的高危人群。我们的目标是确定当相关风险得到妥善管理时,LH是否是治疗CRF合并AUB患者的一个好选择。

材料与方法

本研究纳入了2013年至2016年间因异常子宫出血接受LH手术的5例患者。采用了强化的围手术期管理和技术,以使LH对患者的风险降至最低。

结果

所有患者均成功接受LH手术,围手术期无器官衰竭、严重感染或腹腔出血。手术时间为95至152分钟(平均时间117.6分钟)。术中平均失血量为24毫升。在18个月的随访期内未观察到复发。

结论

对于不再希望保留生育能力的CRF合并AUB患者,子宫切除术可能是一个更好的选择,不仅可以永久解决问题,还可以消除未来子宫病变的风险。改进后的方案将因患者并存的医疗问题而产生的腹腔镜检查的特定风险降至最低,使LH成为CRF合并AUB患者的一种可行治疗方法。

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