Author Affiliations: Department of Nursing, Woosong University, Daejeon (Dr Lee); and College of Nursing Science and East-West Nursing Research Institute, Kyung Hee University, Seoul (Dr Jeong), Korea.
Cancer Nurs. 2019 Nov/Dec;42(6):475-483. doi: 10.1097/NCC.0000000000000645.
Quality of life (QOL) is important for cancer patients, even for survival. However, factors affecting QOL of non-small cell lung cancer (NSCLC) patients have not been studied sufficiently.
The aims of this study were to understand the relationships among social support, resilience, distress, and symptom and to identify predictors of QOL for NSCLC patients.
Participants were 212 adult patients who visited an outpatient department at a tertiary hospital located in Seoul, Korea. Data were collected using self-reported questionnaires and clinical records.
Social support, resilience, distress, symptom burden, and QOL explained 99.9% of the variance in QOL. Social support was not a significant predictor of distress and QOL, but a significant predictor of resilience. Resilience was a significant predictor of both distress and QOL. Distress was not a significant predictor of QOL, but a significant predictor of symptom burden. Symptom burden was a significant predictor of QOL and had the largest direct effect on QOL. Resilience also had an important impact on QOL because resilience influenced QOL in various paths.
This study suggests that social support, resilience, distress, and symptom burden are predictors of QOL in an NSCLC population. These predictors had direct and indirect effects on each other and on QOL.
Developing an interventional program to increase resilience and social support as well as to decrease symptom burden and distress may be necessary to improve QOL of NSCLC patients.
生活质量（QOL）对癌症患者很重要，即使对生存也是如此。然而，影响非小细胞肺癌（NSCLC）患者 QOL 的因素尚未得到充分研究。
本研究旨在了解社会支持、韧性、困扰、症状之间的关系，并确定 NSCLC 患者 QOL 的预测因素。
参与者为 212 名成年患者，他们在韩国首尔的一家三级医院的门诊就诊。数据通过自填式问卷和临床记录收集。
社会支持、韧性、困扰、症状负担和 QOL 解释了 QOL 方差的 99.9%。社会支持不是困扰和 QOL 的显著预测因素，但却是韧性的显著预测因素。韧性是困扰和 QOL 的重要预测因素。困扰不是 QOL 的显著预测因素，但却是症状负担的重要预测因素。症状负担是 QOL 的重要预测因素，对 QOL 具有最大的直接影响。韧性对 QOL 也有重要影响，因为韧性在各种路径上影响 QOL。
本研究表明，社会支持、韧性、困扰和症状负担是 NSCLC 人群 QOL 的预测因素。这些预测因素相互之间以及与 QOL 之间存在直接和间接影响。
为提高 NSCLC 患者的 QOL，可能需要制定干预计划以增加韧性和社会支持，同时减轻症状负担和困扰。
