Department of Obstetrics & Gynecology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada.
Obstet Gynecol. 2018 Oct;132(4):956-959. doi: 10.1097/AOG.0000000000002875.
Although uterine artery embolization has been established as a less invasive alternative to hysterectomy or myomectomy for the treatment of uterine leiomyomas, it is not devoid of life-threatening complications.
We present the case of a 44-year-old patient who developed a severe systemic inflammatory response and acute respiratory distress syndrome 5 weeks after uterine artery embolization of a large multileiomyomatous uterus. Deterioration of her clinical status prompted an emergency hysterectomy that led to rapid improvement.
Although fatalities from septicemia after uterine artery embolization have been reported, aseptic inflammatory responses to uterine degeneration can also lead to multiorgan failure. With recent studies refuting uterine size and leiomyoma location as risk factors, further research is needed to help select appropriate uterine artery embolization candidates.
尽管子宫动脉栓塞术已被确立为治疗子宫肌瘤的一种较子宫切除术或肌瘤切除术创伤更小的替代方法，但它并非没有危及生命的并发症。
我们报告了一例 44 岁患者的病例，该患者在接受大型多发性子宫肌瘤子宫动脉栓塞 5 周后发生严重的全身炎症反应和急性呼吸窘迫综合征。她的临床状况恶化促使进行紧急子宫切除术，这导致病情迅速改善。
尽管有报道称子宫动脉栓塞后败血症导致死亡，但子宫退变的无菌性炎症反应也可导致多器官衰竭。最近的研究反驳了子宫大小和肌瘤位置是危险因素的观点，因此需要进一步研究以帮助选择合适的子宫动脉栓塞候选者。
