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[存活蛙肾近端小管中有机酸钠依赖性转运机制的动力学分析。I. 无钠环境中荧光素和铀的转运]

[Kinetic analysis of mechanisms of Na+-dependent transport of organic acids in the proximal tubules of surviving frog kidney. I. Transport of fluorescein and uranin in a sodium-free environment].

作者信息

Bresler V M, Nikiforov A A

出版信息

Tsitologiia. 1977;19(1):82-9.

PMID:302050
Abstract

By direct microfluorimetry, the kinetic characteristics of active transport system for organic acid were studied. A removal of sodium from the incubation medium is shown to affect the affinity between a carrier and acids (KS), and the rate of translocation of the transporting complex (which includes a carrier and a substrate) across the plasma membrane. The data obtained are in good accordance with the concept of Na+-dependent transport.

摘要

通过直接显微荧光测定法,研究了有机酸主动转运系统的动力学特性。结果表明,从孵育培养基中去除钠会影响载体与酸之间的亲和力(KS),以及转运复合物(包括载体和底物)跨质膜的转运速率。所得数据与钠依赖性转运的概念高度相符。

相似文献

1
[Kinetic analysis of mechanisms of Na+-dependent transport of organic acids in the proximal tubules of surviving frog kidney. I. Transport of fluorescein and uranin in a sodium-free environment].[存活蛙肾近端小管中有机酸钠依赖性转运机制的动力学分析。I. 无钠环境中荧光素和铀的转运]
Tsitologiia. 1977;19(1):82-9.
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Double dependence of organic acid active transport in proximal tubules of surviving frog kidney on sodium ions. I. Influence of sodium ions in bath medium on the uptake and run out of fluorescein and uranin.存活蛙肾近端小管中有机酸主动转运对钠离子的双重依赖性。I. 浴液介质中钠离子对荧光素和铀酸钠摄取及排出的影响。
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[A direct microfluorimetric study of organic acid passage through the proximal tubule cells of the surviving Rana temporaria frog kidney].[对存活的林蛙肾脏近端小管细胞中有机酸转运的直接显微荧光研究]
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Double dependence of organic acid active transport in proximal tubules of surviving frog kidney on sodium ions. II. Relationship between counter-flows of fluorescein and sodium ion across cell layer.存活蛙肾近端小管中有机酸主动转运对钠离子的双重依赖性。II. 荧光素与钠离子跨细胞层逆向流动之间的关系。
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Effect of acetate on transport of organic acid (fluorescein) in renal proximal tubules of frog.
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