Mena-Sánchez G, Babio N, Martínez-González M Á, Corella D, Schröder H, Vioque J, Romaguera D, Martínez J A, Lopez-Miranda J, Estruch R, Wärnberg J, Bueno-Cavanillas A, Serra-Majem L, Tur J A, Arós F, Tinahones F J, Sánchez V M, Lapetra J, Pintó X, Vidal J, Vázquez C, Ordovás J M, Delgado-Rodriguez M, Matía-Martín P, Basora J, Buil-Cosiales P, Fernandez-Carrion R, Fitó M, Salas-Salvadó J
Human Nutrition Unit, University Hospital of Sant Joan de Reus, Department of Biochemistry and Biotechnology, Pere Virgili Institute for Health Research, Rovira i Virgili University, Reus, Spain; CIBER de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
Human Nutrition Unit, University Hospital of Sant Joan de Reus, Department of Biochemistry and Biotechnology, Pere Virgili Institute for Health Research, Rovira i Virgili University, Reus, Spain; CIBER de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
Nutr Metab Cardiovasc Dis. 2018 Oct;28(10):1002-1011. doi: 10.1016/j.numecd.2018.05.006. Epub 2018 May 21.
Fermented dairy products have been associated with a better diet quality and cardio-metabolic profile. However, in Mediterranean populations, these associations have not been well characterized. The aim of this study was to assess the diet quality and the associations between the consumption of total fermented dairy products and their subtypes and the prevalence of Metabolic Syndrome (MetS) components in a Mediterranean population at high cardiovascular risk.
Baseline cross-sectional analyses were conducted on 6,572 men and women (mean age: 65 years) with overweight or obesity and MetS recruited into the PREDIMED-Plus cohort. A 143-item Food Frequency Questionnaire (FFQ) was used, and anthropometrical, biochemical, and blood pressure measurements were recorded. Multivariate-adjusted Cox regressions were fitted to analyze the association between quartiles of consumption of fermented dairy products and their subtypes and MetS components to estimate the relative risk (RR) and 95% confidence intervals (95% CIs). Participants who were high consumers of fermented dairy products reported a higher consumption of fruit, vegetables, fish, nuts, and whole bread and a lower consumption of white bread, alcohol, and cookies. Participants in the higher quartile showed a lower prevalence of the low HDL-cholesterol component of the MetS (RR=0.88; 95% CI: 0.78-0.98) than those in the lowest quartile of cheese consumption. Cheese consumption was inversely associated with the prevalence of hypertriglyceridemia. Total fermented dairy products, yogurt, and its types were not associated with any of the MetS components.
Compared to nonconsumers, participants consuming fermented dairy products reported a better diet quality and, particularly, cheese consumers presented a lower prevalence of hypertriglyceridemia and low HDL-cholesterol plasma levels, which are MetS components.
发酵乳制品与更好的饮食质量和心血管代谢状况相关。然而,在地中海人群中,这些关联尚未得到充分描述。本研究的目的是评估地中海地区心血管疾病高风险人群的饮食质量,以及总发酵乳制品及其亚型的摄入量与代谢综合征(MetS)各组分患病率之间的关联。
对纳入PREDIMED-Plus队列的6572名超重或肥胖且患有MetS的男性和女性(平均年龄:65岁)进行基线横断面分析。使用了一份包含143个条目的食物频率问卷(FFQ),并记录了人体测量、生化和血压测量数据。采用多变量调整的Cox回归分析发酵乳制品及其亚型摄入量四分位数与MetS各组分之间的关联,以估计相对风险(RR)和95%置信区间(95%CI)。发酵乳制品高摄入量的参与者报告水果、蔬菜、鱼类、坚果和全麦面包的摄入量较高,而白面包、酒精和饼干的摄入量较低。与奶酪摄入量最低四分位数的参与者相比,较高四分位数的参与者MetS中低高密度脂蛋白胆固醇组分的患病率较低(RR = 0.88;95%CI:0.78 - 0.98)。奶酪摄入量与高甘油三酯血症的患病率呈负相关。总发酵乳制品、酸奶及其类型与任何MetS组分均无关联。
与不食用者相比,食用发酵乳制品的参与者报告的饮食质量更好,尤其是食用奶酪的参与者高甘油三酯血症患病率较低,且血浆高密度脂蛋白胆固醇水平较低,而这些都是MetS的组分。