Bandzhiulene S Iu, Matulis A A
Ter Arkh. 1986;58(7):46-9.
The content of cAMP in blood T and B lymphocytes was measured in 30 patients with rheumatoid arthritis (RA), 10 patients with systemic lupus erythematosus (SLE) and 28 donors. A statistically significant increase in the cAMP content in T lymphocytes of RA and SLE patients was established. On the contrary, in B lymphocytes of blood of RA patients and of SLE patients, in particular, the cAMP content was below normal. In female patients with RA, the cAMP content in T lymphocytes was appreciably higher than in male patients.
对30例类风湿性关节炎（RA）患者、10例系统性红斑狼疮（SLE）患者和28名献血者的血液T淋巴细胞和B淋巴细胞中的环磷酸腺苷（cAMP）含量进行了测定。结果发现，RA和SLE患者T淋巴细胞中的cAMP含量有统计学意义的升高。相反，尤其是RA患者和SLE患者血液中的B淋巴细胞，其cAMP含量低于正常水平。在女性RA患者中，T淋巴细胞中的cAMP含量明显高于男性患者。
