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猪细小病毒疫苗的效力

Efficacy of porcine parvovirus vaccines.

作者信息

Edwards K R, Emmerson M A, Luff P R, Wells D E, Muskett J C, Wrathall A E, Richardson C, Parker B N, Thornton D H

出版信息

Vet Rec. 1986 Aug 30;119(9):203-6. doi: 10.1136/vr.119.9.203.

Abstract

Three inactivated porcine parvovirus vaccines were tested for efficacy in 66 susceptible gilts. The gilts were challenged with virulent virus on the 40th day of gestation. All the vaccines provided excellent protection against fetal mortality despite insignificant serological responses to one of them. Good protection was obtained with two of the vaccines even when the dose was substantially reduced. Unvaccinated controls had very few viable fetuses.

摘要

对三种灭活猪细小病毒疫苗在66头易感后备母猪中进行了效力测试。这些后备母猪在妊娠第40天用强毒病毒进行攻毒。尽管其中一种疫苗的血清学反应不显著,但所有疫苗都对胎儿死亡提供了极佳的保护。即使大幅降低剂量,其中两种疫苗仍能提供良好的保护。未接种疫苗的对照组存活胎儿极少。

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