Mádr V, Mádr P
Vet Med (Praha). 1986 Oct;31(10):599-608.
An inactivated vaccine against swine parvovirosis with a lipoid adjuvant was tested in a herd infested with parvoviruses. The titre of the haemagglutination-inhibition antibodies was studied at the time of the first pregnancy in two groups of gilts included in the herd at the age of 7.5 months - one group vaccinated, the other left untreated. In the vaccinated group the geometrical means of the titres were significantly higher than in the non-vaccinated group throughout the time of study. The difference in the average number of piglets per litter between the two groups was evaluated after parturition. On an average, the gilts of the vaccinated group had 1.5 more live pigs per litter (P less than 0.05). As also found, when the antibody titre increases by log 10, the number of piglets per litter increases by 1.55. On the basis of the results the vaccination of gilts against swine parvovirosis in endemically infested herds is considered an efficient preventive measure having a high economic effect.
一种含类脂佐剂的猪细小病毒病灭活疫苗在感染细小病毒的猪群中进行了试验。对该猪群中7.5月龄的两组后备母猪,在首次怀孕时研究了血凝抑制抗体滴度——一组接种疫苗,另一组不进行处理。在整个研究期间,接种疫苗组的滴度几何平均值显著高于未接种疫苗组。分娩后评估了两组每窝仔猪的平均数量差异。平均而言,接种疫苗组的后备母猪每窝多产1.5头活猪(P<0.05)。还发现,当抗体滴度以对数10增加时,每窝仔猪数量增加1.55头。基于这些结果,在地方性感染猪群中对后备母猪接种猪细小病毒病疫苗被认为是一种具有高经济效益的有效预防措施。