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经胆囊腹腔镜胆总管探查失败的预测因素:多中心综合卫生系统数据库分析

Predictors of Failed Transcystic Laparoscopic Common Bile Duct Exploration: Analysis of Multicenter Integrated Health System Database.

作者信息

Al-Temimi Mohammed H, Rangarajan Sriram, Chandrasekaran Bindupriya, Kim Edwin G, Trujillo Charles N, Mousa Asrai F, Santos David A, Johna Samir D

机构信息

1 Arrowhead Regional Medical Center, Colton, California.

2 Kaiser Permanente Fontana Medical Center, Fontana, California.

出版信息

J Laparoendosc Adv Surg Tech A. 2019 Mar;29(3):360-365. doi: 10.1089/lap.2018.0360. Epub 2018 Sep 12.

Abstract

BACKGROUND

The aim of this study is to report our experience with laparoscopic common bile duct exploration (LCBDE) and validate the experts' opinion about anatomical predictors of failed transcystic LCBDE (TLCBDE) approach.

METHODS

Patients undergoing LCBDE at Kaiser Permanente Southern California hospitals (2005-2015) were included. Predictors of failed TLCBDE were identified using bivariate analysis.

RESULTS

Of 115 LCBDE, 89.6% were TLCBDE and 10.4% through choledochotomy. Success rate, morbidity, and length of hospital stay were 83.5%, 6.1%, and 3.8 days respectively. Only stone size:cystic duct ratio >1 (35% versus 63%, P = .044) was associated with failure of TLCBDE. In accordance with experts' opinion, there was a suggestive association of stone size ≥6 mm, cystic duct ≤4 mm, multiple stones, and proximal stone location with failure; however, these did not reach statistical significance.

CONCLUSION

LCBDE is an effective and safe mean of clearing common bile duct stones at community hospitals of an integrated health system. Previously cited contraindications for TLCBDE are not absolute, but rather predictors of failure.

摘要

背景

本研究旨在报告我们行腹腔镜胆总管探查术(LCBDE)的经验,并验证专家关于经胆囊管腹腔镜胆总管探查术(TLCBDE)失败的解剖学预测因素的观点。

方法

纳入在南加州凯撒医疗集团医院接受LCBDE的患者(2005 - 2015年)。采用双变量分析确定TLCBDE失败的预测因素。

结果

在115例LCBDE中,89.6%为TLCBDE,10.4%为胆总管切开术。成功率、发病率和住院时间分别为83.5%、6.1%和3.8天。仅结石大小与胆囊管直径之比>1(35%对63%,P = 0.044)与TLCBDE失败相关。与专家观点一致,结石大小≥6 mm、胆囊管≤4 mm、多发结石和结石位于近端与失败存在提示性关联;然而,这些未达到统计学意义。

结论

在综合医疗系统的社区医院中,LCBDE是清除胆总管结石的一种有效且安全的方法。先前引用的TLCBDE的禁忌证并非绝对,而是失败的预测因素。

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