Department of Surgery, Denver Health Medical Center, Denver, CO, USA.
Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Surg Endosc. 2024 Oct;38(10):6076-6082. doi: 10.1007/s00464-024-11139-5. Epub 2024 Aug 13.
Advancements in laparoscopic techniques led to the adoption of laparoscopic common bile duct exploration (LCBDE) as an alternative to endoscopic retrograde cholangiopancreatography (ERCP) for management of choledocholithiasis (CD). The goal of this study was to describe the initial experience at a safety net hospital with acute care surgeons performing LCBDE for suspected CD. We hypothesized LCBDE would reduce length of stay and hospital costs compared to laparoscopic cholecystectomy (LC) and ERCP performed in the same hospital admission.
This was a retrospective case-control study from 2019 to 2023 comparing LCBDE to LC/ERCP among patients diagnosed with CD. Statistical analyses were performed using Mann-Whitney U tests for continuous variables and Chi-square tests for categorical variables. Data reported as median [interquartile range] or research subjects with condition (percentage).
A total of 110 LCBDE were performed, while 121 subjects underwent LC and ERCP. Patients in the LCBDE group were more likely to be female with a total of 87 female subjects (77.6%) compared to 76 male subjects (62.8%) (95% CI 1.14-3.74). Initial WBC was lower in the LCBDE group at 8.4 [6.9-11.8] compared to the LC/ERCP group at 10.9 [7.9-13.5] (p = 0.0013). Remaining demographics and lab values were similar between the two groups. Patients who underwent LCBDE had a significantly shorter length of stay at 2 days [1-3] compared to those in the LC/ERCP group at 4 days [3-6] (p < 0.001). Hospital charges for the LCBDE group were $46,685 [$38,687-$56,703] compared to $60,537 [$47,527-$71,739] for the LC/ERCP group (p < 0.001).
LCBDE is associated with significantly lower hospital costs and shorter length of stay with similar post-operative complication and 30-day readmission rates. Our results show that LCBDE is safe and should be considered as a first-line approach in the management of CD.
腹腔镜技术的进步使得腹腔镜胆总管探查术(LCBDE)成为治疗胆总管结石(CD)的一种替代内镜逆行胰胆管造影术(ERCP)的方法。本研究的目的是描述一家急救医院的急性护理外科医生进行 LCBDE 治疗疑似 CD 的初步经验。我们假设与在同一住院期间进行的腹腔镜胆囊切除术(LC)和 ERCP 相比,LCBDE 可降低住院时间和住院费用。
这是一项回顾性病例对照研究,纳入了 2019 年至 2023 年期间诊断为 CD 的患者,比较了 LCBDE 与 LC/ERCP。连续变量采用 Mann-Whitney U 检验,分类变量采用卡方检验。数据以中位数[四分位数范围]或具有某种情况的研究对象(百分比)报告。
共进行了 110 例 LCBDE,121 例患者接受了 LC 和 ERCP。LCBDE 组患者中女性患者居多,共 87 例(77.6%),而 LC/ERCP 组为 76 例(62.8%)(95%CI 1.14-3.74)。LCBDE 组的初始白细胞计数(WBC)为 8.4[6.9-11.8],而 LC/ERCP 组为 10.9[7.9-13.5](p=0.0013)。两组间其他人口统计学和实验室值相似。LCBDE 组的住院时间明显短于 LC/ERCP 组,分别为 2 天[1-3]和 4 天[3-6](p<0.001)。LCBDE 组的住院费用为 46685 美元[38687-56703],而 LC/ERCP 组为 60537 美元[47527-71739](p<0.001)。
LCBDE 与显著较低的住院费用和较短的住院时间相关,术后并发症和 30 天再入院率相似。我们的结果表明,LCBDE 是安全的,应考虑作为治疗 CD 的一线方法。