National Institute of Information and Communications Technology, Koganei, Tokyo, 184-8795, Japan.
Phys Med Biol. 2018 Oct 16;63(20):205008. doi: 10.1088/1361-6560/aae0e5.
Coaxial sensors are effective for measurement of dielectric properties of biological tissues. Several measurement methods used to derive dielectric properties have been investigated for the measurement with a coaxial sensor at microwave frequencies. While the measurement accuracy depends on the method used, there has been insufficient intercomparison of these methods and their model approximation errors. On the other hand, we have developed a coaxial sensor for the measurement of complex permittivity at millimeter-wave (MMW) frequencies of up to 100 GHz. However, the scarcity of reference data at MMW frequencies makes the validation of the measurement system difficult. Thus, it is essential to clarify the model approximation error of the method used in the measurement system, particularly at MMW frequencies. This study aims to clarify the model approximation errors of methods for dielectric property measurement using a coaxial sensor at MMW frequencies. The model approximation errors were assessed by comparing results obtained by the methods with those based on the theoretical formula of the full-wave modal expression of Maxwell's equations. The measurement uncertainty for the theoretical formula was estimated for a standard liquid sample to clarify the contribution of the model approximation errors to the uncertainty. Furthermore, the methods were applied to the measurement of porcine tissues at body temperature, and the measurement accuracy and usability for measurement at MMW frequencies are discussed.
同轴传感器在测量生物组织的介电特性方面非常有效。已经研究了几种用于微波频率下同轴传感器测量的介电特性测量方法。虽然测量精度取决于所使用的方法,但这些方法之间的相互比较及其模型近似误差还不够充分。另一方面,我们已经开发出一种用于测量毫米波 (MMW) 频率高达 100 GHz 的复介电常数的同轴传感器。然而,在 MMW 频率下参考数据的缺乏使得测量系统的验证变得困难。因此,必须澄清测量系统中所使用方法的模型近似误差,特别是在 MMW 频率下。本研究旨在澄清在 MMW 频率下使用同轴传感器进行介电特性测量的方法的模型近似误差。通过将方法获得的结果与基于麦克斯韦方程全波模态表达式的理论公式的结果进行比较,评估了模型近似误差。为了澄清模型近似误差对不确定性的贡献,对标准液体样品的理论公式的测量不确定度进行了估计。此外,该方法还应用于猪组织在体温下的测量,并讨论了在 MMW 频率下测量的准确性和可用性。