Mycobacterium marinum infection in gnotobiotic nu/nu mice pretreated with cyclophosphamide and silica.
作者信息
Burchard G D, Engelhorn S, Zillmann U, Dietrich M
出版信息
Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Jul;261(4):411-6. doi: 10.1016/s0176-6724(86)80072-4.
PMID:3020845
Abstract
Germfree nude mice (NMRJ-nu/nu) and germfree nu/+ mice were infected with Mycobacterium marinum in the footpad test. After pretreatment with 400 mg/kg cyclophosphamide, significantly higher amounts of M. marinum were reached in the footpad and in the liver. On the other hand, the yield of M. marinum could not be elevated by in vivo inhibition of macrophages with silica.
摘要
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