Kubín M, Holub M, Mohelská H, Schlegerová D
Exp Pathol. 1984;25(4):233-44. doi: 10.1016/s0232-1513(84)80025-0.
Subcutaneous infection with Mycobacterium kansasii did not cause mortality in athymic nu/nu and control nu/+ mice. It had a stimulatory activity comparable to obligatory mycobacterial pathogens: thymus-dependent lymphatic tissues areas were populated during the infection by lymphocytes also in nu/nu mice in which a low degree of migration inhibition factor production could be seen. In both models of chief site of mycobacterial trapping and phagocytosis was the hyperplastic interdigitating cell mesh in the thymus-dependent areas of lymph nodes. A detailed morphological description of the organ changes is given.
堪萨斯分枝杆菌皮下感染在无胸腺裸鼠(nu/nu)和对照杂合鼠(nu/+)中均未导致死亡。它具有与 obligatory 分枝杆菌病原体相当的刺激活性:在感染期间,nu/nu 小鼠的胸腺依赖性淋巴组织区域也有淋巴细胞聚集,且这些小鼠可产生低度的迁移抑制因子。在两种模型中,淋巴结胸腺依赖性区域增生的指状突细胞网是分枝杆菌捕获和吞噬的主要部位。文中给出了器官变化的详细形态学描述。