• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

无胸腺裸鼠感染堪萨斯分枝杆菌的实验性感染

Experimental infection with Mycobacterium kansasii in athymic nude mice.

作者信息

Kubín M, Holub M, Mohelská H, Schlegerová D

出版信息

Exp Pathol. 1984;25(4):233-44. doi: 10.1016/s0232-1513(84)80025-0.

DOI:10.1016/s0232-1513(84)80025-0
PMID:6540715
Abstract

Subcutaneous infection with Mycobacterium kansasii did not cause mortality in athymic nu/nu and control nu/+ mice. It had a stimulatory activity comparable to obligatory mycobacterial pathogens: thymus-dependent lymphatic tissues areas were populated during the infection by lymphocytes also in nu/nu mice in which a low degree of migration inhibition factor production could be seen. In both models of chief site of mycobacterial trapping and phagocytosis was the hyperplastic interdigitating cell mesh in the thymus-dependent areas of lymph nodes. A detailed morphological description of the organ changes is given.

摘要

堪萨斯分枝杆菌皮下感染在无胸腺裸鼠(nu/nu)和对照杂合鼠(nu/+)中均未导致死亡。它具有与 obligatory 分枝杆菌病原体相当的刺激活性:在感染期间,nu/nu 小鼠的胸腺依赖性淋巴组织区域也有淋巴细胞聚集,且这些小鼠可产生低度的迁移抑制因子。在两种模型中,淋巴结胸腺依赖性区域增生的指状突细胞网是分枝杆菌捕获和吞噬的主要部位。文中给出了器官变化的详细形态学描述。

相似文献

1
Experimental infection with Mycobacterium kansasii in athymic nude mice.无胸腺裸鼠感染堪萨斯分枝杆菌的实验性感染
Exp Pathol. 1984;25(4):233-44. doi: 10.1016/s0232-1513(84)80025-0.
2
Lymphatic tissues of nude mice during early stages of Mycobacterium kansasii infection.
Folia Biol (Praha). 1978;24(6):428-9.
3
Mycobacterium marinum infection in gnotobiotic nu/nu mice pretreated with cyclophosphamide and silica.
Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Jul;261(4):411-6. doi: 10.1016/s0176-6724(86)80072-4.
4
Disseminated atypical mycobacteriosis in a child--a case of Mycobacterium sculoflaseum.儿童播散性非典型分枝杆菌病——一例海分枝杆菌感染病例
Acta Pathol Jpn. 1978 Sep;28(5):751-8. doi: 10.1111/j.1440-1827.1978.tb00914.x.
5
Immune responsiveness in mice heavily infected with Mycobacterium kansasii.重度感染堪萨斯分枝杆菌的小鼠的免疫反应性。
Immunology. 1984 Oct;53(2):357-64.
6
Response of congenitally athymic (nude) mice to infection with Mycobacterium bovis (strain BCG).先天性无胸腺(裸)小鼠对牛分枝杆菌(卡介苗菌株)感染的反应。
J Natl Cancer Inst. 1975 Jun;54(6):1419-26. doi: 10.1093/jnci/54.6.1419.
7
Changes in proliferation activity and relative distributions of lymphoid cell subpopulations in congenitally athymic nu/nu mice and Lurcher mice with spontaneous olivopontocerebellar degeneration.先天性无胸腺裸鼠和患有自发性橄榄脑桥小脑变性的Lurcher小鼠中淋巴细胞亚群的增殖活性和相对分布的变化。
Folia Microbiol (Praha). 2006;51(5):497-505. doi: 10.1007/BF02931598.
8
Disseminated atypical mycobacteriosis.播散性非典型分枝杆菌病
Acta Pathol Jpn. 1984 Mar;34(2):459-69. doi: 10.1111/j.1440-1827.1984.tb07574.x.
9
Sporotrichoid spread of cutaneous Mycobacterium chelonei infection.皮肤龟分枝杆菌感染的孢子丝菌病样播散
Clin Exp Dermatol. 1989 Jul;14(4):309-12. doi: 10.1111/j.1365-2230.1989.tb01990.x.
10
Progressive and fatal infection with attenuated Mycobacterium bovis (BCG) in nude mice.卡介苗(BCG)减毒株在裸鼠中引起的进行性致死性感染。
Jpn J Exp Med. 1978 Dec;48(6):533-43.