Suppr超能文献

桑拿排毒对药物滥用迁延性戒断症状的安全性和耐受性。

Safety and tolerability of sauna detoxification for the protracted withdrawal symptoms of substance abuse.

作者信息

Lennox Richard D, Cecchini-Sternquist Marie

机构信息

Chestnut Global Partners, Chestnut Health Systems, Martin Luther King Drive, Bloomington, Illinois, USA.

出版信息

J Int Med Res. 2018 Nov;46(11):4480-4499. doi: 10.1177/0300060518779314. Epub 2018 Sep 13.

Abstract

OBJECTIVE

Protracted drug withdrawal symptoms can last months or years after drug cessation, often precipitating a return to substance misuse. We evaluated the safety and preliminary health benefits of a unique chemical exposure regimen based on exercise, sauna and therapeutic nutrients.

METHODS

This was a prospective evaluation of 109 individuals sequentially enrolled into a sauna detoxification component of a multi-modal, long-term residential substance abuse treatment centre.

RESULTS

Data from medical charts, client self-reports and Short Form Health Survey (SF-36) responses indicated that the Hubbard sauna detoxification method was well tolerated, with a 99% completion rate, including one human immunodeficiency virus and nine hepatitis C positive clients. There were no cases of dehydration, overhydration or heat illness. Statistically significant improvements were seen in both mental and physical SF-36 scores at regimen completion, as well as in Addiction Severity Index and Global Appraisal of Individual Needs Short Screener change scores at rehabilitation program discharge, compared with enrolment.

CONCLUSIONS

The regimen lacked serious adverse events, had a very low discontinuation rate and high client-reported satisfaction. The SF-36 data indicated improved physical and emotional symptoms. Therefore, broader investigation of this sauna-based treatment regimen is warranted.

摘要

目的

长期药物戒断症状在停药后可持续数月或数年,常常促使患者重新滥用药物。我们评估了一种基于运动、桑拿和治疗性营养物质的独特化学暴露方案的安全性和初步健康益处。

方法

这是一项对109名依次纳入一个多模式、长期住院药物滥用治疗中心桑拿排毒项目的个体进行的前瞻性评估。

结果

来自病历、患者自我报告和简短健康调查问卷(SF-36)回答的数据表明,哈伯德桑拿排毒法耐受性良好,完成率为99%,其中包括1名人类免疫缺陷病毒感染者和9名丙型肝炎阳性患者。未出现脱水、水合过度或热疾病病例。与入组时相比,在方案完成时,SF-36心理和生理评分以及康复项目出院时的成瘾严重程度指数和个体需求总体评估简短筛查量表变化评分均有统计学意义的改善。

结论

该方案没有严重不良事件,停药率极低,患者报告的满意度高。SF-36数据表明身体和情绪症状有所改善。因此,有必要对这种基于桑拿的治疗方案进行更广泛的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1d5/6259397/e29a45026ccd/10.1177_0300060518779314-fig1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验