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患有持续性自然获得性猫白血病病毒感染的猫的免疫特征

Immunologic profiles of cats with persistent, naturally acquired feline leukemia virus infection.

作者信息

Reimann K A, Bull R W, Crow S E, Coffman P, Raskin R E

出版信息

Am J Vet Res. 1986 Sep;47(9):1935-9.

PMID:3021028
Abstract

Several immunologic responses were measured in 13 healthy cats with naturally acquired, persistent feline leukemia virus (FeLV) viremia from 4 multiple-cat households and were compared with responses from 28 of their healthy, non-FeLV-viremic housemates. Significant differences (P = less than 0.05) were not observed between results of FeLV-viremic and nonviremic cats for peripheral blood leukocyte or lymphocyte count, percentage of peripheral blood mononuclear cells able to form rosettes with guinea pig RBC or with antibody- and complement-coated sheep RBC, lymphocyte proliferative response to concanavalin A or pokeweed mitogen, or serum immunoglobulin G concentration. Seemingly, persistent FeLV viremia, when naturally acquired, may exist for some time without lymphopenia or a marked loss of mitogen-induced lymphocyte proliferation.

摘要

对来自4个多猫家庭的13只自然感染持续性猫白血病病毒(FeLV)血症的健康猫进行了几种免疫反应检测,并与它们28只健康、无FeLV血症的同屋猫的反应进行了比较。FeLV血症猫和非血症猫在外周血白细胞或淋巴细胞计数、能够与豚鼠红细胞或抗体和补体包被的绵羊红细胞形成玫瑰花结的外周血单个核细胞百分比、对刀豆球蛋白A或商陆有丝分裂原的淋巴细胞增殖反应或血清免疫球蛋白G浓度的检测结果之间未观察到显著差异(P<0.05)。显然,自然获得的持续性FeLV血症可能在一段时间内存在而不伴有淋巴细胞减少或丝裂原诱导的淋巴细胞增殖明显丧失。

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