神经降压素、纳洛酮和氟哌啶醇对促肾上腺皮质激素诱导的过度梳理行为要素的影响。
The influence of neurotensin, naloxone, and haloperidol on elements of excessive grooming behavior induced by ACTH.
作者信息
van Wimersma Greidanus T B, Maigret C, Ten Haaf J A, Spruijt B M, Colbern D L
出版信息
Behav Neural Biol. 1986 Sep;46(2):137-44. doi: 10.1016/s0163-1047(86)90612-6.
Naloxone, haloperidol, and neurotensin suppress ACTH-induced grooming. The suppressive effects of naloxone and of haloperidol on ACTH-induced grooming are observed following subcutaneous as well as intracerebroventricular administration. The suppression of ACTH-induced grooming by these drugs is not accompanied by a change in the relative distribution of grooming elements. From previous data and from the results of the present study it is suggested that the underlying substrate involved in ACTH-induced excessive grooming may differ from that of bombesin-induced grooming.
纳洛酮、氟哌啶醇和神经降压素可抑制促肾上腺皮质激素（ACTH）诱导的梳理行为。皮下注射以及脑室内注射后，均可观察到纳洛酮和氟哌啶醇对ACTH诱导的梳理行为的抑制作用。这些药物对ACTH诱导的梳理行为的抑制作用并未伴随梳理行为元素相对分布的改变。根据先前的数据和本研究的结果，提示ACTH诱导的过度梳理行为所涉及的潜在底物可能与蛙皮素诱导的梳理行为的底物不同。
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