Department of Chemistry , University of Copenhagen , Universitetsparken 5 , DK-2100 Copenhagen Ø , Denmark.
Org Lett. 2018 Sep 21;20(18):5821-5825. doi: 10.1021/acs.orglett.8b02518. Epub 2018 Sep 13.
Tweezer-like molecules comprised of two boron subphthalocyanine (SubPc) units were prepared by Sonogashira couplings and investigated using NMR spectroscopy for their ability to bind fullerenes (C and C). The preorganization of the tweezers provided association constants of ca. 10 M in toluene- d, while a SubPc monomer did not show any association. Nevertheless, the SubPc monomer crystallized with the fullerenes as 2:1 complexes, supporting the favorable tweezer-like design for complexation, which was further corroborated by computations.
由两个硼亚酞菁（SubPc）单元组成的镊子状分子是通过 Sonogashira 偶联反应制备的，并通过 NMR 光谱研究了它们与富勒烯（C 和 C）结合的能力。镊子的预组织提供了在甲苯-d 中约 10 M 的结合常数，而 SubPc 单体则没有表现出任何缔合。然而，SubPc 单体与富勒烯结晶形成 2:1 配合物，支持了有利于配合物形成的类似镊子的设计，这一结论进一步得到了计算的证实。
