Cheng Christina Wh, Wong Clara Sm, Hui Grace Km, Chung Edmond Kn, Wong Steven Hs
Department of Anaesthesiology, Queen Elizabeth Hospital, Hong Kong.
Pain Manag. 2018 Sep 1;8(5):377-388. doi: 10.2217/pmt-2018-0024. Epub 2018 Sep 13.
Fibromyalgia is a chronic pain syndrome of unclear pathophysiology. It is believed to be a dysfunction of the CNS, but no definite structural lesion has been identified so far. Despite a number of changes in the diagnostic criteria, diagnosis remains a clinical one. Since the 2011 revision of the IASP definition of neuropathic pain, fibromyalgia has been excluded from the diagnosis of neuropathic pain. More recent studies however found newer evidences of pathophysiology including small fiber neuropathy in patients with fibromyalgia. This may challenge the existing consensus and have implications on future diagnosis and management of this condition.
纤维肌痛是一种病理生理学尚不明确的慢性疼痛综合征。人们认为它是中枢神经系统功能障碍，但迄今为止尚未发现明确的结构性病变。尽管诊断标准有诸多变化，但诊断仍基于临床判断。自2011年国际疼痛研究协会（IASP）对神经性疼痛定义进行修订以来，纤维肌痛已被排除在神经性疼痛诊断之外。然而，最近的研究发现了纤维肌痛患者病理生理学的新证据，包括小纤维神经病变。这可能会挑战现有的共识，并对该疾病未来的诊断和管理产生影响。
