Rao R K, Ramakrishnan C V
Biol Neonate. 1986;50(3):165-70. doi: 10.1159/000242595.
Inositol phosphatase and phytase activities in different segments of the rat small intestine were measured during postnatal development. In the duodenum and jejunum, inositol phosphatase activity (units/g tissue) was low during the suckling period and increased at weaning, reaching a peak of activity at 4 weeks of age. In the ileum, peak activity was observed during the suckling period with a sharp decline at weaning. Phytase activity was very low during the suckling period in all segments, and increased to exhibit a peak at 4 weeks of age in the duodenum, and to a lesser extent in the jejunum (low activity was maintained in the ileum). The content of inositol phosphatase activity in the duodenum increased rapidly during the suckling period to reach its maximum at 4 weeks of age. This suggests a relationship to cell proliferation rate in the small intestinal mucosa.
在出生后发育过程中，对大鼠小肠不同节段的肌醇磷酸酶和植酸酶活性进行了测定。在十二指肠和空肠中，肌醇磷酸酶活性（单位/克组织）在哺乳期较低，断奶时增加，在4周龄时达到活性峰值。在回肠中，峰值活性在哺乳期观察到，断奶时急剧下降。植酸酶活性在哺乳期所有节段都非常低，在十二指肠中4周龄时增加至峰值，在空肠中增加程度较小（回肠中维持低活性）。十二指肠中肌醇磷酸酶活性的含量在哺乳期迅速增加，在4周龄时达到最大值。这表明与小肠黏膜中的细胞增殖率有关。
