用于白塞病的草药医学（甘草泻心汤）：一项系统评价方案。
Herbal medicine (Gancao Xiexin decoction) for Behcet disease: A systematic review protocol.
作者信息
Wu Dongjie, Lin Weiwei, Wong Ka-Wang
机构信息
School of Chinese Medicine, Hong Kong Baptist University, Hong Kong Graduate School, Zhejiang Chinese Medical University, Hangzhou The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang Province Department of Chemistry, Hong Kong Baptist University, Hong Kong SAR, China.
出版信息
Medicine (Baltimore). 2018 Sep;97(37):e12324. doi: 10.1097/MD.0000000000012324.
BACKGROUND
Behcet disease (BD) is a systemic vasculitis that causes blood vessel inflammation throughout body and no cure exists. The purpose of this review is to evaluate the safety and efficacy of Gancao Xiexin Decoction (GCXX) in the treatment of BD and provide a clinical reference for the treatment of the refractory disease.
METHODS
First, the researcher will retrieve the following database based on the established search strategy: MEDLINE (PubMed), the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, Allied and Complementary Medicine Database (AMED), China National Knowledge Infrastructure, Wanfang, VIP (Journal Integration Platform). The quality of the literature will be evaluated according to Cochrane's handbook and review inclusion criteria. Data will be extracted and data of sufficient homogeneity was combined using Review Manager (RevMan) software V5.3.5.
RESULTS
This study will provide a high quality synthesis of herbal medicine (Gancao Xiexin decoction) for Behcet disease.
CONCLUSIONS
The conclusion of our systematic review will provide evidence to judge whether herbal medicine (Gancao Xiexin decoction) for Behcet disease is an effective intervention for patient with menopausal women.
TRIAL REGISTRATION NUMBER
PROSPERO CRD 42018104099.
背景
白塞病（BD）是一种全身性血管炎，可导致全身血管炎症，且尚无治愈方法。本综述的目的是评估甘草泻心汤（GCXX）治疗白塞病的安全性和有效性，并为难治性疾病的治疗提供临床参考。
方法
首先，研究人员将根据既定的检索策略检索以下数据库：医学文献数据库（PubMed）、Cochrane系统评价数据库（CENTRAL）、荷兰医学文摘数据库（EMBASE）、补充与替代医学数据库（AMED）、中国知网、万方数据库、维普资讯网（期刊整合平台）。将根据Cochrane手册和综述纳入标准评估文献质量。提取数据，并使用Review Manager（RevMan）软件V5.3 .5合并具有充分同质性的数据。
结果
本研究将为白塞病的草药（甘草泻心汤）提供高质量的综合分析。
结论
我们系统评价的结论将为判断治疗白塞病的草药（甘草泻心汤）是否是绝经女性患者的有效干预措施提供证据。
试验注册号
PROSPERO CRD 42018104099。
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