Scott J W
Brain Res. 1977 Aug 26;132(2):247-58. doi: 10.1016/0006-8993(77)90419-x.
A technique for measurement of small samples of unit behavior during regularly repeated stimulation is described. A correlation-based measure was computed over two successive stimulus presentation by summing the products of spike counts for corrsponding time bins and normalizing to the number of bins and the number of spike counts during the two stimulus presentations. This measure was combined with the mean frequency of spike occurrence during the stimulus presentation to give a characterization of neuronal activity sensitive to changes in both strength of temporal patterns and mean frequency. Examples are given of olfactory responsive neurons with comparison of measurement techniques. The time course of the response to odor of neurons recorded under urethane anesthesia from the olfactory bulb and the lateral hypothalamus was studied. By both simple mean frequency measures and the measures proposed in this study, the neurons recorded from the lateral hypothalamus underwent more rapid temporal decrements in the odor response.
本文描述了一种在定期重复刺激期间测量单位行为小样本的技术。通过对两个连续刺激呈现过程中相应时间间隔内的脉冲计数乘积求和，并归一化到时间间隔数量和两个刺激呈现期间的脉冲计数数量，计算出基于相关性的测量值。该测量值与刺激呈现期间脉冲出现的平均频率相结合，以表征对时间模式强度和平均频率变化均敏感的神经元活动。给出了嗅觉反应神经元的示例，并比较了测量技术。研究了在氨基甲酸乙酯麻醉下从嗅球和外侧下丘脑记录的神经元对气味反应的时间进程。通过简单的平均频率测量和本研究中提出的测量方法，发现从外侧下丘脑记录的神经元在气味反应中经历了更快的时间衰减。
