Ruffin R, Alpers J H, Kroemer D K, Rubinfeld A R, Pain M C, Czarny D, Bowes G
Eur J Respir Dis Suppl. 1986;147:336-9.
The use of nedocromil sodium 4 mg q.i.d. in asthmatics with mildly unstable asthma induced by a reduction of their inhaled beclomethasone dipropionate dose was investigated in a double-blind, parallel group, placebo-controlled study. Compared with placebo, nedocromil sodium improved night-time and daytime asthma score, night-time and daytime bronchodilator use, and evening PEFR at some stage during the 4-week treatment. It is concluded that nedocromil sodium exerts a beneficial effect in chronic asthma.
在一项双盲、平行组、安慰剂对照研究中，对使用4毫克奈多罗米钠每日4次治疗因吸入丙酸倍氯米松剂量减少而导致轻度哮喘不稳定的哮喘患者进行了调查。与安慰剂相比，在4周治疗的某个阶段，奈多罗米钠改善了夜间和白天的哮喘评分、夜间和白天支气管扩张剂的使用情况以及傍晚的呼气峰流速（PEFR）。得出的结论是，奈多罗米钠对慢性哮喘有有益作用。
