Bhasipol Adikan, Sanjaroensuttikul Nopawan, Pornsuriyasak Prapaporn, Yamwong Sukit, Tangcharoen Tarinee
Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Department of Rehabilitation Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Congenit Heart Dis. 2018 Nov;13(6):952-958. doi: 10.1111/chd.12659. Epub 2018 Sep 14.
We aimed to study the efficiency and safety of once-a-week outpatient rehabilitation followed by home program with tele-monitoring in patients with complex cyanotic congenital heart disease.
Prospective nonrandomized study.
Patients who have been diagnosed either Eisenmenger's syndrome or inoperable complex cyanotic heart disease and able to attend 12-week cardiac rehabilitation program were included. Training with treadmill walking and bicycling under supervision at cardiac rehabilitation unit once-a-week in the first 6 weeks followed by home-based exercise program (bicycle and walking) with a target at 40%-70% of maximum heart rate (HRmax) at pretraining peak exercise for another 6 weeks was performed in the intervention group. Video and telephone calls were scheduled for evaluation of compliance and complication. Data from cardiopulmonary exercise testing (CPET) on cycle ergometry including peak oxygen consumption (peakVO ), oxygen pulse (O pulse), ventilatory equivalent for carbon dioxide (VE/CO at anaerobic threshold), constant work-rate endurance time (CWRET) at 75% of peak VO , and 6-minute walk distance (6MWD) were compared between baseline and after training by paired t test.
Of the 400 patients in our adult congenital heart disease clinic, 60 patients met the inclusion criteria. Eleven patients who could follow program regularly were assigned home program. There was a statistically significant improvement of CWRET, O₂ pulse, and 6MWD after finishing the program (P = .003, .039, and .001, respectively). The mean difference of 6MWD change in the home-program group was significantly higher than in the control group (69.3 ± 47.9 meters vs. 4.1 ± 43.4 meters, P = .003). No serious adverse outcomes were reported during home training.
Once-a-week outpatient hospital-based exercise program followed by supervised home-based exercise program showed a significant benefit in improvement of exercise capacity in adults with complex cyanotic congenital heart disease without serious adverse outcomes.
我们旨在研究对于患有复杂性青紫型先天性心脏病的患者,每周一次门诊康复治疗并辅以家庭计划及远程监测的有效性和安全性。
前瞻性非随机研究。
纳入已被诊断为艾森曼格综合征或无法手术的复杂性青紫型心脏病且能够参加为期12周心脏康复计划的患者。干预组在前6周每周一次在心脏康复单元接受跑步机行走和骑自行车训练,训练由专人监督,之后的6周进行家庭锻炼计划(骑自行车和行走),目标是达到训练前峰值运动时最大心率(HRmax)的40%-70%。安排视频和电话通话以评估依从性和并发症情况。通过配对t检验比较基线和训练后在自行车测力计上进行心肺运动测试(CPET)的数据,包括峰值耗氧量(peakVO₂)、氧脉搏(O₂脉搏)、无氧阈时二氧化碳通气当量(VE/CO₂)、峰值VO₂的75%时的恒定工作率耐力时间(CWRET)以及6分钟步行距离(6MWD)。
在我们成人先天性心脏病门诊的400名患者中,60名患者符合纳入标准。11名能够定期遵循计划的患者被分配到家庭计划组。完成计划后,CWRET、O₂脉搏和6MWD有统计学意义的改善(P分别为0.003、0.039和0.001)。家庭计划组6MWD变化的平均差异显著高于对照组(69.3±47.9米对4.1±43.4米,P = 0.003)。家庭训练期间未报告严重不良后果。
每周一次的门诊医院锻炼计划,随后进行有监督的家庭锻炼计划,对于改善患有复杂性青紫型先天性心脏病的成年人的运动能力有显著益处,且无严重不良后果。