Oña-Ortiz F M, Sánchez-Del Monte J, Ramírez-Solís M E, de la Mora-Levy J G, Alonso-Larraga J O, Lino-Silva L S, Herrera-Servín M A, Jiménez-Morales M, Manzano-Robleda M C, Yañez-Cruz M, Hernández-Guerrero A I
Departamento de Endoscopia Gastrointestinal, Instituto Nacional de Cancerología, Secretaría de Salud, Ciudad de México, México.
Departamento de Endoscopia Gastrointestinal, Instituto Nacional de Cancerología, Secretaría de Salud, Ciudad de México, México.
Rev Gastroenterol Mex (Engl Ed). 2019 Oct-Dec;84(4):434-441. doi: 10.1016/j.rgmx.2018.07.001. Epub 2018 Sep 11.
Mantle cell lymphoma is an aggressive subtype of B-cell non-Hodgkin lymphoma and its incidence is 0.5/100,000 inhabitants. Gastrointestinal involvement at diagnosis is 15-30%. The aim of our study was to analyze the clinical and endoscopic characteristics of mantle cell lymphoma affecting the digestive tract.
A retrospective study was conducted, based on a case series of patients with mantle cell lymphoma affecting the gastrointestinal tract that were diagnosed over a 10-year period.
Ten patients (11.7%) had gastrointestinal tract involvement. The upper endoscopic findings were polypoid lesions (66%), thickened folds (44%), and nonspecific changes in the mucosa (33%). At colonoscopy, polypoid lesions were viewed in 100% of the patients and ulcerated lesions in 40%.
Polypoid lesions are the most common endoscopic characteristics in patients with mantle cell lymphoma of the gastrointestinal tract. Upper endoscopy and colonoscopy should be carried out on patients with mantle cell lymphoma, even those with nonspecific symptoms, to check their gastrointestinal status. Gastrointestinal involvement has an impact on disease staging.
套细胞淋巴瘤是B细胞非霍奇金淋巴瘤的一种侵袭性亚型，其发病率为每10万居民中有0.5例。诊断时胃肠道受累率为15% - 30%。本研究的目的是分析影响消化道的套细胞淋巴瘤的临床和内镜特征。
基于一个10年间诊断为影响胃肠道的套细胞淋巴瘤患者的病例系列进行回顾性研究。
10例患者（11.7%）有胃肠道受累。上消化道内镜检查结果为息肉样病变（66%）、皱襞增厚（44%）和黏膜非特异性改变（33%）。结肠镜检查时，100%的患者可见息肉样病变，40%的患者可见溃疡样病变。
息肉样病变是胃肠道套细胞淋巴瘤患者最常见的内镜特征。对于套细胞淋巴瘤患者，即使是那些有非特异性症状的患者，也应进行上消化道内镜检查和结肠镜检查，以检查其胃肠道状况。胃肠道受累对疾病分期有影响。
