GlaxoSmithKline Worldwide Epidemiology, Research Triangle Park, North Carolina; Department of Epidemiology, University of North Carolina at Chapel Hill, Research Triangle Park, North Carolina.
GlaxoSmithKline Worldwide Epidemiology, Collegeville, Pennsylvania.
J Am Acad Dermatol. 2018 Feb;78(2):358-362. doi: 10.1016/j.jaad.2017.10.004. Epub 2017 Oct 6.
Population-based and clinical case reports of hyperhidrosis (HH) provide prevalence estimates that vary widely across reported studies because of differences in case ascertainment.
In this study, we specify diagnostic, symptom, and prescription codes for HH to estimate incidence and prevalence for the United Kingdom and the United States.
Data from UK and US health care databases were analyzed to ascertain HH cases and estimate incidence and prevalence from health care records during calendar years 2011 through 2013.
On the basis of 2013 data for the United States and United Kingdom, between 1.0% and 1.6% of these populations have health care records indicating diagnosis or treatment of HH. Women accounted for approximately 60% of incident and prevalent cases in both databases.
Because the case ascertainment methods rely on available data for those seeking health care, we may have underestimated the number of HH cases in both countries.
The findings represent a plausible estimate for incidence and prevalence of HH among persons seeking medical care for excessive sweating. Improved practices for identifying HH in clinical settings may increase the sensitivity and specificity of future studies and improve characterization and quantification of the population burden of this significant disease.
基于人群的和临床病例报告提供的多汗症（HH）患病率估计值因病例确定方法的不同而差异很大。
本研究旨在为英国和美国指定 HH 的诊断、症状和处方代码，以估计发病率和患病率。
分析了来自英国和美国医疗保健数据库的数据，以确定 HH 病例，并根据 2011 年至 2013 年的医疗记录估计发病率和患病率。
根据 2013 年美国和英国的数据，这两个国家约有 1.0%至 1.6%的人群的医疗记录表明有 HH 的诊断或治疗。在两个数据库中，女性约占新发和现患病例的 60%。
由于病例确定方法依赖于寻求医疗保健的人群的现有数据，因此我们可能低估了这两个国家 HH 病例的数量。
这些发现代表了寻求医疗护理以治疗过度出汗的人群中 HH 的发病率和患病率的合理估计。改进临床环境中 HH 的识别方法可能会提高未来研究的敏感性和特异性，并改善这种重大疾病的人群负担的特征和量化。
