Department of Pathology, Hopital Tenon, HUEP, Sorbonne University, Paris, France.
Department of Urology, Hospital Motol and 2nd Faculty of Medicine, Charles University, Prague, Czech Republic.
World J Urol. 2019 Jan;37(1):41-50. doi: 10.1007/s00345-018-2466-5. Epub 2018 Sep 14.
Many changes have been made during these last years and concepts for understanding bladder cancer have evolved. We make an update with the latest findings of the WHO (World Health Organistaion) 2016, ICCR (International Collaboration on Cancer Reporting) and other official organisms and try to show the latest developments. In this document we provide new consensus guidelines and insights. We kept this document short and concise providing consensus guidelines to clinicians for the best patient care, it should be easy to understand for a non pathologists. We focussed on several burning issues, such as the anatomical and histological understanding of the bladder wall, the prognostic significance of grading and the most challenging problems in staging, we underline our needs from the clinicians such as clinical information, we further discuss the histological subtypes of bladder cancer, which is an extremely important issue in the light of molecular classifications and give prognostic insights. Furthermore, we discuss the ICCR worldwide consensus reporting, urinary cytology with the Paris system and several issues such as frozen section specimen.
在过去的几年中，已经发生了许多变化，对膀胱癌的理解也有所发展。我们根据世界卫生组织（WHO）2016 年、国际癌症报告合作组织（ICCR）和其他官方机构的最新发现进行了更新，并尝试展示最新的发展。在本文档中，我们提供了新的共识指南和见解。我们保持文档简短明了，为临床医生提供最佳患者护理的共识指南，以便非病理学家也能轻松理解。我们关注了几个热点问题，如膀胱壁的解剖和组织学理解、分级的预后意义以及分期中最具挑战性的问题，强调了我们对临床医生的需求，如临床信息，我们进一步讨论了膀胱癌的组织学亚型，鉴于分子分类，这是一个极其重要的问题，并提供了预后见解。此外，我们还讨论了 ICCR 全球共识报告、巴黎系统的尿细胞学以及冷冻切片标本等几个问题。
