MRC Unit for Lifelong Health and Ageing at UCL, 33 Bedford Place, London, WC1B 5JU, UK.
Population, Policy and Practice, UCL Great Ormond Street Hospital Institute of Child Health, University College London, London, WC1N 1EH, UK.
Int J Behav Nutr Phys Act. 2018 Sep 15;15(1):89. doi: 10.1186/s12966-018-0723-z.
To identify whether changes in adult health and social factors are associated with simultaneous changes in inactivity.
Health, social factors and leisure-time inactivity (activity frequency < 1/week) were self-reported at 33y and 50y in the 1958 British birth cohort (N = 12,271). Baseline (33y) health and social factors and also patterns of change in factors 33y-to-50y were related to inactivity 33y-to-50y (never inactive, persistently inactive, deteriorating to inactivity, or improving from inactivity) using multinomial logistic regression.
Approximately 31% were inactive at 33y and 50y; 35% changed status 33y-to-50y (17% deteriorating to inactivity, 18% improving from inactivity). Baseline poor health and obesity were associated with subsequent (33y-to-50y) inactivity; e.g. for poor health, relative risk ratios (RRRs) for deteriorating to inactivity (vs never inactive) and improving from inactivity (vs persistently inactive) were 1.38(1.16,1.64) and 0.77(0.63,0.94) respectively. Adverse changes in health and weight were associated with simultaneous adverse changes in inactivity; e.g. worsening health (vs always good/excellent health) was associated with higher risk of deteriorating to inactivity (RRR:2.20(1.85,2.62)) and lower risk of improving from inactivity (RRR:0.61(0.49,0.77)). However, improving health and weight loss were not associated with improving from inactivity. Worsening self-efficacy 33y-to-50y was associated with lower risk of improving from inactivity; there was no association between improving self-efficacy and inactivity change. Downward social mobility was not associated with deteriorating to or improving from inactivity. Changes in depression symptom level, marriage/co-habitation or parenthood 33y-to-50y were not associated with inactivity changes. No associations were observed for employment.
Associated changes in mid-life health factors with deleterious inactivity changes, highlight the importance of maintaining health, weight and self-efficacy across adulthood to deter inactivity.
为了确定成年人健康和社会因素的变化是否与同时发生的不活动有关。
1958 年英国出生队列（N=12271）在 33 岁和 50 岁时自我报告健康、社会因素和休闲时间不活动（活动频率<1/周）。使用多项逻辑回归分析，将基线（33 岁）健康和社会因素以及 33 岁至 50 岁期间的因素变化模式与 33 岁至 50 岁期间的不活动（从不不活动、持续不活动、恶化至不活动或从不不活动改善）相关联。
约 31%的人在 33 岁和 50 岁时不活动；35%的人在 33 岁至 50 岁期间改变了状态（17%恶化至不活动，18%从不不活动改善）。基线健康状况差和肥胖与随后（33 岁至 50 岁）的不活动有关；例如，对于健康状况差，恶化至不活动（与从不不活动相比）和从不不活动改善（与持续不活动相比）的相对风险比（RRR）分别为 1.38（1.16，1.64）和 0.77（0.63，0.94）。健康和体重的不利变化与不活动的同时不利变化有关；例如，健康状况恶化（与始终良好/优秀的健康状况相比）与恶化至不活动的风险增加（RRR：2.20（1.85，2.62））和从不不活动改善的风险降低（RRR：0.61（0.49，0.77））有关。然而，改善健康和减肥与从不不活动改善无关。33 岁至 50 岁期间自我效能的恶化与从不不活动改善的风险降低有关；自我效能的改善与不活动变化之间没有关联。社会地位的下降与恶化或从不不活动改善无关。33 岁至 50 岁期间抑郁症状水平、婚姻/同居或父母身份的变化与不活动变化无关。就业没有观察到关联。
中年健康因素的相关变化与有害的不活动变化有关，这突显了在整个成年期保持健康、体重和自我效能的重要性，以阻止不活动。
