Quesada J R, Reuben J, Hopfer R L, Mundon F K, Hersh E M
Leuk Res. 1986;10(10):1169-73. doi: 10.1016/0145-2126(86)90234-1.
Serum from 60 patients with hairy cell leukemia (HCL) were studied for the presence and the titers of antibodies to Epstein-Barr virus (EBV), cytomegalovirus (CMV) and human T-cell lymphotrophic viruses (HTLV). Eighty-three percent of the patients were seropositive for EBV, with a (reciprocal) geometric mean titer (GMT) of 960. Seventy-eight percent of the patients had antibodies to CMV with a GMT of 435. All 21 patients tested for HTLV I and HTLV III were seronegative; only one patient showed detectable antibodies to HTLV II. The potential role of these infections in the physiopathology of HCL is discussed.
对60例毛细胞白血病（HCL）患者的血清进行了研究，以检测抗爱泼斯坦-巴尔病毒（EBV）、巨细胞病毒（CMV）和人类T细胞嗜淋巴细胞病毒（HTLV）抗体的存在情况及滴度。83%的患者EBV血清学呈阳性，几何平均滴度（GMT）（倒数）为960。78%的患者有抗CMV抗体，GMT为435。所有检测HTLV I和HTLV III的21例患者血清学均为阴性；仅1例患者显示可检测到的抗HTLV II抗体。讨论了这些感染在HCL生理病理学中的潜在作用。
