Vuillemin M, Pexieder T, Janecek P, Stamm H
Microsurgery. 1986;7(3):138-45. doi: 10.1002/micr.1920070309.
The purpose of this study is to show by SEM the characteristics of mucosal healing related to the presence of intraluminal sutures of nylon (nonabsorbable) or dexon (absorbable) in the rabbit oviduct. Altogether, 30 animals with anastomosis in the isthmus were killed 2, 4, 8, or 12 weeks after the operation. Tubular structures or pieces of thread partially or completely covered by the epithelium were found n 36.8% of these cases. Independently of the suture material used, already 2 weeks after surgery, the thread was covered by an epithelium composed mostly of squamous cells and some rare ciliated cells. At 4 weeks, the proportion of ciliated cells was increased. Regions with the usual cellular morphology and repartition of the different cellular types were also observed. However, at 8 and 12 weeks, islets of atypical squamous cells persisted in areas of transmucosal passage of the suture material. At 12 weeks, the dexon suture was not yet completely absorbed.
本研究的目的是通过扫描电子显微镜展示兔输卵管内尼龙（不可吸收）或聚乙醇酸（可吸收）腔内缝合线的存在与黏膜愈合特征之间的关系。总共30只在峡部进行吻合术的动物在术后2、4、8或12周被处死。在这些病例中，36.8%发现了部分或完全被上皮覆盖的管状结构或线片段。无论使用何种缝合材料，术后仅2周，缝线就被主要由鳞状细胞和一些罕见的纤毛细胞组成的上皮覆盖。4周时，纤毛细胞的比例增加。还观察到具有不同细胞类型的正常细胞形态和分布的区域。然而，在8周和12周时，非典型鳞状细胞岛持续存在于缝合材料经黏膜通过的区域。12周时，聚乙醇酸缝线尚未完全吸收。
