Nelson April M, Martin Irwin G, Getz Kenneth A
1 Eastern Michigan University, Ypsilanti, MI, USA.
2 Center for the Study of Drug Development, Tufts University School of Medicine, Boston, MA, USA.
Ther Innov Regul Sci. 2015 Nov;49(6):940-946. doi: 10.1177/2168479015583727.
It is widely acknowledged that patient recruitment is a significant challenge and represents one of the primary reasons for drug development delays. Data from the Center for Information and Study on Clinical Research Participation (CISCRP) "Perceptions & Insights" study indicate that the 18- to 34-year-old Generation Y subgroup was the least willing to participate in a clinical trial.
The willingness of Generation Y to participate in clinical studies was compared to that of older groups in the CISCRP study. These results were then compared to data from earlier studies.
Statistically significant differences existed between the willingness of Generation Y to participate in clinical studies when compared to older age groups. Generational perceptions and value differences were explored via corporate and sociological research findings to determine why disparities existed among age groups regarding the willingness for clinical trial participation.
Preliminary results indicate that members of Generation Y are less willing to participate in clinical studies and that these differences are truly generational and not simply age related.
众所周知，患者招募是一项重大挑战，也是药物研发延迟的主要原因之一。临床研究参与信息与研究中心（CISCRP）“认知与见解”研究的数据表明，18至34岁的Y世代亚组最不愿意参与临床试验。
在CISCRP研究中，将Y世代参与临床研究的意愿与年龄较大的组进行了比较。然后将这些结果与早期研究的数据进行了比较。
与年龄较大的组相比，Y世代参与临床研究的意愿存在统计学上的显著差异。通过企业和社会学研究结果探讨了代际认知和价值差异，以确定各年龄组在参与临床试验意愿方面存在差异的原因。
初步结果表明，Y世代成员不太愿意参与临床研究，而且这些差异是真正的代际差异，而不仅仅与年龄相关。
