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胆管恶性肿瘤的内镜超声检查及局部可切除性的术前评估

Endoscopic ultrasonography of bile duct malignancy and the preoperative assessment of local resectability.

作者信息

Tio T L, Tytgat G N

出版信息

Scand J Gastroenterol Suppl. 1986;123:151-7. doi: 10.3109/00365528609091877.

Abstract

Endoscopic ultrasonography (EUS) was performed before surgery in 12 patients with Klatskin tumour and in 8 patients with distal common bile duct carcinoma. The usual EUS findings consisted of an intraductular mass lesion together with adjacent lymph node involvement. The depth of malignant infiltration into the surrounding tissues could clearly be seen, which was of utmost importance in assessing local resectability. A clearly demarcated malignant growth with or without evidence of loco-regional lymph node involvement was considered compatible with local resectability. Involvement of distant lymph nodes along major blood vessels was thought to indicate palliative resection. Evidence of deep infiltration of the malignancy into the surrounding tissues (mesenteric artery, coeliac trunk, aorta) and/or organs (liver metastasis) was considered to indicate non-resectability. From this study EUS appears to be a sensitive modality for detecting, staging, and preoperative assessment of local resectability in bifurcation tumours and in distal bile duct malignancy. Technical improvements enabling guided cytological puncture and reducing the length of the rigid tip may further enhance its diagnostic value.

摘要

对12例肝门部胆管癌患者和8例胆总管远端癌患者在手术前进行了内镜超声检查(EUS)。EUS的常见表现包括导管内肿块病变以及相邻淋巴结受累。能清楚地看到恶性肿瘤向周围组织浸润的深度,这对评估局部可切除性至关重要。有或无局部区域淋巴结受累证据的界限清楚的恶性肿瘤生长被认为与局部可切除性相符。沿主要血管的远处淋巴结受累被认为提示姑息性切除。恶性肿瘤向周围组织(肠系膜动脉、腹腔干、主动脉)和/或器官(肝转移)的深度浸润证据被认为提示不可切除。从这项研究来看,EUS似乎是检测、分期以及术前评估肝门部肿瘤和远端胆管恶性肿瘤局部可切除性的一种敏感方法。能够实现引导性细胞学穿刺并缩短硬性探头长度的技术改进可能会进一步提高其诊断价值。

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