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急性缺血性血栓形成的管理

Management of Acute Ischemic Thrombosis.

作者信息

Vakharia Kunal, Atwal Gursant S, Levy Elad I

机构信息

Department of Neurosurgery, University at Buffalo, 100 High Street, B4, Buffalo, NY 14203, USA.

Department of Neurosurgery, University at Buffalo, 100 High Street, B4, Buffalo, NY 14203, USA; Clinical and Translational Research Center, CSRVC, 875 Ellicott Street, Buffalo, NY 14214, USA.

出版信息

Neurosurg Clin N Am. 2018 Oct;29(4):595-604. doi: 10.1016/j.nec.2018.06.012. Epub 2018 Aug 14.

Abstract

Acute ischemic thrombosis in patients who have undergone neurosurgical procedures is a leading cause of mortality and long-term disability. Endovascular therapy has become an important treatment modality for acute ischemic thrombosis in these patients. Noninvasive imaging has dramatically changed the understanding of cerebral blood flow and the concepts of cerebrovascular reserve and salvageable penumbra. Increasingly, reliance on perfusion imaging to discern tissue viability and potential outcomes has become standard of care. With the advent of recent acute ischemic stroke trials, therapy for occlusive cerebrovascular disease is evolving, and understanding when to intervene is becoming paramount.

摘要

接受神经外科手术后发生的急性缺血性血栓形成是导致死亡和长期残疾的主要原因。血管内治疗已成为这些患者急性缺血性血栓形成的重要治疗方式。无创成像极大地改变了人们对脑血流的理解以及脑血管储备和可挽救半暗带的概念。越来越多地,依靠灌注成像来辨别组织活力和潜在结果已成为标准治疗方法。随着近期急性缺血性中风试验的出现,闭塞性脑血管疾病的治疗正在不断发展,而了解何时进行干预变得至关重要。

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