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玻璃体切除术联合后段艾哈迈德瓣膜植入术:一项病例系列研究。

Vitrectomy combined with posterior-segment Ahmed valve implant: A case series study.

作者信息

de Frutos-Lezaun M, Rodriguez-Agirretxe I, Eder Labairu F, Irigoyen C

机构信息

Donostia University Hospital - Hospital Universitario Donostia, 117 Beguiristain Street, San Sebastian 20080, Spain.

Instituto Clínico-Quirúrgico de Oftalmología (ICQO), 34 Begoñako Andra Maria Street, Bilbao 48006, Spain.

出版信息

Saudi J Ophthalmol. 2018 Jul-Sep;32(3):180-187. doi: 10.1016/j.sjopt.2018.03.002. Epub 2018 Mar 15.

Abstract

PURPOSE

To analyze the surgical outcomes and complication rates in a group of patients with refractory glaucoma who underwent simultaneous pars plana vitrectomy (PPV) and PC7 or PC8 Ahmed glaucoma valve (AGV) implantation.

METHODS

Retrospective case series study of 10 eyes in 9 patients with secondary glaucoma, refractory to other treatment, who underwent 23G-PPV and implantation of PC7 or PC8 AGV between 2012 and 2014. Study variables were postoperative BCVA, IOP and the number of glaucoma medications, which were evaluated preoperatively and at 1 day, 1 week and 1, 3, 6, and 12 months after the surgical intervention. Absolute success was defined as IOP less than 21 mmHg in the absence of any medication and qualified success if medication was needed to control IOP under 21 mmHg.

RESULTS

The average follow-up was 10.2 ± 2.89 months. Postoperative IOP levels decreased in all cases in comparison with preoperative values (p < 0.05). Absolute success rate was 60%, reaching 100% in terms of qualified success. Kaplan-Meier survival analysis showed 60% absolute success at 12 months. Changes in postoperative BCVA were not statistically significant in comparison with preoperative data. Early postoperative complications were athalamia, hyphema, and retinal detachment; late complications were pars plana clip extrusion and cystic bleb.

CONCLUSIONS

PC7 and PC8 Ahmed valve implantation via pars plana is a safe and useful option in patients with secondary refractory glaucoma who are either candidates for PPV or have been previously vitrectomized.

摘要

目的

分析一组难治性青光眼患者同时行玻璃体切割术(PPV)及PC7或PC8型艾哈迈德青光眼引流阀(AGV)植入术的手术效果及并发症发生率。

方法

对2012年至2014年间9例继发性青光眼患者的10只眼进行回顾性病例系列研究,这些患者对其他治疗无效,接受了23G-PPV及PC7或PC8型AGV植入术。研究变量包括术后最佳矫正视力(BCVA)、眼压(IOP)及青光眼药物使用数量,于术前及手术干预后1天、1周、1、3、6和12个月进行评估。绝对成功定义为在未使用任何药物的情况下眼压低于21 mmHg,若需要药物将眼压控制在21 mmHg以下则为合格成功。

结果

平均随访时间为10.2±2.89个月。与术前相比,所有病例术后眼压水平均下降(p<0.05)。绝对成功率为60%,合格成功率达100%。Kaplan-Meier生存分析显示12个月时绝对成功率为60%。与术前数据相比,术后BCVA的变化无统计学意义。术后早期并发症为无晶体眼、前房积血和视网膜脱离;晚期并发症为扁平部夹脱出和囊性滤过泡。

结论

对于适合PPV或既往已行玻璃体切割术的继发性难治性青光眼患者,经扁平部植入PC7和PC8型艾哈迈德引流阀是一种安全有效的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f052/6137825/4261fed17797/gr1.jpg

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