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埃塞俄比亚亚的斯亚贝巴哮喘患者中抑郁症的流行病学及相关因素

Epidemiology of Depression and Associated Factors among Asthma Patients in Addis Ababa, Ethiopia.

作者信息

Woledesenbet Mebrat Abera, Shumet Mekonen Shegaye, Sori Lamesa Melese, Abegaz Tadesse Melaku

机构信息

University of Gondar Hospital, College of Medicine and Health Sciences, Department of Psychiatry, Ethiopia.

University of Gondar, College of Medicine and Health Sciences, Department of Psychiatry, Ethiopia.

出版信息

Psychiatry J. 2018 Aug 26;2018:5934872. doi: 10.1155/2018/5934872. eCollection 2018.

Abstract

BACKGROUND

Depression in asthma patients can cause worsening of respiratory symptoms. Addressing mental illness in those with asthma improves asthma outcomes. This study aimed to assess the epidemiology of depression and associated factors among asthma patients attending government hospitals in Ethiopia.

METHODS

Institutional based cross-sectional study was conducted on patients with asthma at three governmental hospitals of Addis Ababa from June to July 2017. Patient health questionnaire (PHQ-9) depression scale was used to assess prevalence of depression among asthmatic patients. The data were entered and analyzed using SPSS version 20 statistical software. Binary logistic regression analysis was conducted to identify associated factors for depression. To indicate the strength of association, odds ratios (OR) and 95% confidence intervals (95% CI) were used.

RESULT

A total of 405 participants were enrolled in the study giving an overall response rate of 96%. The respondents had mean age of 54.46 and standard deviation (SD) of 10.01 years. About 273 (67.4%) were females. The prevalence of depression among asthma patients was 85 (21%). The odds of developing depression among single asthma patients were increased by 1.63 with 95% CI [1. 8, 3.493]. Depression among asthma patients who had comorbid cardiac illness was 6.2 times higher than those who do not have at CI [1.145, 24.109]. The prevalence of depression among uncontrolled asthma patients was 8 times higher than those with well-controlled asthma at CI [1.114, 19.025].

CONCLUSION

One-fifth of asthmatic patients were experiencing depression. Uncontrolled asthma, comorbid cardiac illness, and single patients were important predictors of depression among asthmatic patients. Proper control of asthmatic attack and cardiac illnesses is very important to reduce the burden of depression.

摘要

背景

哮喘患者的抑郁会导致呼吸道症状恶化。解决哮喘患者的精神疾病问题可改善哮喘治疗效果。本研究旨在评估埃塞俄比亚政府医院中哮喘患者抑郁的流行病学情况及相关因素。

方法

2017年6月至7月,在亚的斯亚贝巴的三家政府医院对哮喘患者进行了基于机构的横断面研究。采用患者健康问卷(PHQ - 9)抑郁量表评估哮喘患者的抑郁患病率。数据使用SPSS 20版统计软件录入和分析。进行二元逻辑回归分析以确定抑郁的相关因素。为表明关联强度,使用了比值比(OR)和95%置信区间(95%CI)。

结果

共有405名参与者纳入研究,总应答率为96%。受访者的平均年龄为54.46岁,标准差(SD)为10.01岁。约273名(67.4%)为女性。哮喘患者中抑郁的患病率为85例(21%)。单一哮喘患者发生抑郁的几率增加了1.63倍,95%CI为[1.8, 3.493]。合并心脏病的哮喘患者中抑郁发生率比无合并症者高6.2倍,CI为[1.145, 24.109]。未控制的哮喘患者中抑郁患病率比病情控制良好的哮喘患者高8倍,CI为[1.114, 19.025]。

结论

五分之一的哮喘患者存在抑郁。未控制的哮喘、合并心脏病以及单身患者是哮喘患者抑郁的重要预测因素。有效控制哮喘发作和心脏病对于减轻抑郁负担非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3529/6129350/3a4889664aa5/PSYCHIATRY2018-5934872.001.jpg

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