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病例报告:美国一起异尖线虫病的共同来源暴发及家庭接触者的暴露后预防。

Case Report: A Common Source Outbreak of Anisakidosis in the United States and Postexposure Prophylaxis of Family Collaterals.

机构信息

Department of Medicine, School of Medicine, University of California, San Diego, California.

Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.

出版信息

Am J Trop Med Hyg. 2018 Nov;99(5):1219-1221. doi: 10.4269/ajtmh.18-0586.

Abstract

We present a case of intussusception with complete small bowel obstruction caused by intestinal anisakidosis requiring surgical resection. A 30-year-old man presented with acute onset of severe abdominal pain 3 days after eating home-cured salmon gravlax. Despite surgery, the patient developed recurrent abdominal pain on two occasions with evidence of continued inflammation proximal to the surgical anastomosis. He was then treated with albendazole and prednisone, and symptoms improved. A decision was made to prophylactically treat two asymptomatic family members who also consumed home-cured gravlax with albendazole, resulting in one individual passing an intact worm in her stool. We suggest that albendazole therapy could be considered as a therapy for continued symptoms of anisakidosis and postexposure prophylaxis of larvae ingestion from a common source.

摘要

我们报告了一例由肠旋毛虫病引起的完全性小肠梗阻导致的肠套叠,需要手术切除。一名 30 岁男子在食用自制三文鱼 Gravlax 后 3 天突发严重腹痛。尽管进行了手术,但患者在手术吻合口近端仍有持续炎症的证据,出现了两次反复发作的腹痛。随后他接受了阿苯达唑和泼尼松治疗,症状得到改善。我们决定对另外两名也食用了自制 Gravlax 的无症状家庭成员预防性地使用阿苯达唑治疗,结果其中一名个体的粪便中排出了一条完整的虫子。我们建议阿苯达唑治疗可考虑用于治疗持续的旋毛虫病症状以及从共同来源摄入幼虫后的暴露后预防。

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