Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies , North Carolina Agricultural and Technical State University , North Carolina Research Campus, 500 Laureate Way , Kannapolis , North Carolina 28081 , United States.
J Agric Food Chem. 2018 Oct 10;66(40):10347-10352. doi: 10.1021/acs.jafc.8b04110. Epub 2018 Sep 27.
There is growing evidence that whole grain (WG) intake may prevent many chronic diseases. However, there are mixed results on this topic in human studies as a result of a lack of accurate tools to assess the intake of WGs and individual metabolic variation. To better understand the effects of WGs on health maintenance and the risk of chronic disease, there is an urgent need to identify the biomarkers for WG intake. The molecular signatures of WG intake remain undefined. This perspective gives an overview of the current knowledge, challenges, and future directions on the biomarkers of WG intake.
越来越多的证据表明，全谷物（WG）的摄入可能有助于预防许多慢性疾病。然而，由于缺乏准确的工具来评估 WG 的摄入量和个体代谢的差异，人体研究中关于这一主题的结果并不一致。为了更好地了解 WG 对维持健康和预防慢性疾病的影响，迫切需要确定 WG 摄入量的生物标志物。WG 摄入量的分子特征仍不清楚。本文综述了 WG 摄入量生物标志物的现有知识、挑战和未来方向。
