Jones M M, Lidsky M D, Brewer E J, Yow M D, Williamson W D
Arthritis Rheum. 1986 Nov;29(11):1402-4. doi: 10.1002/art.1780291114.
We describe an infant with symptomatic congenital cytomegalovirus infection, who was born to a mother with active systemic lupus erythematosus. Infection in the child resulted from reactivation of maternal cytomegalovirus infection. The mother's use of prednisone may have contributed to the reactivation. The role of maternal immunosuppression in the acquisition of congenital viral infection by the neonate is discussed.
我们描述了一名患有症状性先天性巨细胞病毒感染的婴儿,其母亲患有活动性系统性红斑狼疮。患儿的感染是由于母亲巨细胞病毒感染的重新激活所致。母亲使用泼尼松可能促成了这种重新激活。本文讨论了母亲免疫抑制在新生儿获得先天性病毒感染中的作用。