Thomas Theodore S, Pachynski Russell K
Theodore S. Thomas, MD, MPHS, is a staff Oncologist, St. Louis VA Medical Center, St. Louis, Missouri.
Russell K. Pachynski, MD, is Assistant Professor, Division of Oncology, Washington, University School of Medicine, St. Louis, Missouri.
Mo Med. 2018 Mar-Apr;115(2):156-161.
Advanced prostate cancer is a heterogenous disease with multiple treatment options. Patients with advanced disease are stratified based evidence of metastasis and sensitivity to hormone therapy. Men with hormone sensitive disease are treated with androgen deprivation therapy and possibly chemotherapy. The treatment options for men with castrate resistant disease are rapidly evolving with multiple recently approved treatment options. Determining the proper sequence and combination of these therapies remains a work in progress.
晚期前列腺癌是一种具有多种治疗选择的异质性疾病。晚期疾病患者根据转移证据和对激素治疗的敏感性进行分层。激素敏感型疾病的男性患者接受雄激素剥夺治疗,可能还会接受化疗。去势抵抗性疾病男性患者的治疗选择正在迅速发展,最近有多种获批的治疗方案。确定这些治疗方法的正确顺序和组合仍在不断探索中。