DiNicolantonio James J, Mehta Varshil, Zaman Sojib Bin, O'Keefe James H
James J. DiNicolantonio, PharmD, is at Saint Luke's Mid America Heart Institute, Kansas City, Mo.
Varshil Mehta, MBBS, is with Mount Sinai Hospital, New York and MGM Medical College, Navi Mumbai, India.
Mo Med. 2018 May-Jun;115(3):247-252.
Salt has notoriously been blamed for causing an increase in the urinary excretion of calcium, and thus is a considered a risk factor for osteoporosis. However, the increase in the urinary excretion of calcium with higher sodium intakes can be offset by the increased intestinal absorption of dietary calcium. Thus, the overall calcium balance does not appear to be reduced with a higher sodium intake. However, the other ubiquitous white crystal, sugar, may lead to osteoporosis by increasing inflammation, hyperinsulinemia, increased renal acid load, reduced calcium intake, and increased urinary calcium excretion. Sugar, not salt, is the more likely white crystal to be a risk factor for osteoporosis when overconsumed.
众所周知,盐一直被指责会导致钙的尿排泄增加,因此被认为是骨质疏松症的一个风险因素。然而,随着钠摄入量增加而导致的钙尿排泄增加,可以被膳食钙肠道吸收的增加所抵消。因此,较高的钠摄入量似乎并不会降低总体钙平衡。然而,另一种无处不在的白色晶体——糖,可能会通过增加炎症、高胰岛素血症、增加肾脏酸负荷、减少钙摄入量以及增加尿钙排泄而导致骨质疏松症。过量食用时,糖而非盐更有可能成为骨质疏松症的风险因素。