Hawkins E P, Finegold M J, Hawkins H K, Krischer J P, Starling K A, Weinberg A
Cancer. 1986 Dec 15;58(12):2579-84. doi: 10.1002/1097-0142(19861215)58:12<2579::aid-cncr2820581204>3.0.co;2-v.
Clinical and morphologic features of 89 cases of childhood yolk sac tumor (YS) and embryonal carcinoma (EC) (29 associated with teratomas) submitted to the Rare Tumor Registry of the Southwest Oncology Group (1971-1979) or the Pediatric Oncology Group (1980-1984) between 1971 and 1984 were reviewed and submitted to statistical analysis. This review showed an improved survival for each 5-year period regardless of tumor site, no statistically significant difference between "pure" tumors and those mixed with other teratomatous components, no statistically significant difference between YS and EC in children, a better than reported prognosis for sacrococcygeal tumors occurring after the neonatal period, a particularly poor prognosis for neonatal "benign" sacrococcygeal teratomas resected without coccygectomy when they recur as YS, excellent survival for all testicular tumors regardless of age or the presence of EC, and the occurrence of mediastinal tumors in females.
对1971年至1984年间提交给西南肿瘤协作组罕见肿瘤登记处（1971 - 1979年）或儿科肿瘤协作组（1980 - 1984年）的89例儿童卵黄囊瘤（YS）和胚胎癌（EC）（29例与畸胎瘤相关）的临床和形态学特征进行了回顾，并进行了统计分析。该回顾显示，无论肿瘤部位如何，每5年生存率都有所提高；“单纯”肿瘤与那些与其他畸胎瘤成分混合的肿瘤之间无统计学显著差异；儿童的YS和EC之间无统计学显著差异；新生儿期后发生的骶尾部肿瘤的预后比报告的要好；新生儿“良性”骶尾部畸胎瘤在复发为YS时，若未行尾骨切除术而切除，预后特别差；所有睾丸肿瘤无论年龄或是否存在EC，生存率都很高；以及女性纵隔肿瘤的发生情况。
