Kaste S C, Bridges J O, Marina N M
Department of Diagnostic Imaging, St. Jude Children's Research Hospital, 332 N. Lauderdale, P. O. Box 318, Memphis, TN 38101-0318, USA.
Pediatr Radiol. 1996;26(3):212-9. doi: 10.1007/BF01405303.
Sacrococcygeal teratomas and their malignant counterparts (germ cell tumors) are the most common solid tumors in neonates. Prompt diagnosis is essential because the frequency of malignant transformation increases from 10-20 % in neonates to 67 % in patients over 2 months of age. Cross-sectional imaging has largely replaced surgical exploration for staging these tumors and assessing their response to chemotherapy. Radiologists must be familiar with changes in the imaging findings of these tumors during and after treatment so that they can advise clinicians regarding the efficacy of therapy and the presence or absence of recurrent disease. From our study, magnetic resonance imaging appears to be a better modality for assessing sacral invasion and metastases and distinguishing fibrotic masses from recurrent tumor.
骶尾部畸胎瘤及其恶性对应物（生殖细胞肿瘤）是新生儿中最常见的实体瘤。及时诊断至关重要，因为恶性转化的频率从新生儿的10%-20%增加到2个月以上患者的67%。横断面成像在很大程度上已取代手术探查用于这些肿瘤的分期及评估其对化疗的反应。放射科医生必须熟悉这些肿瘤在治疗期间及治疗后的影像学表现变化，以便就治疗效果及是否存在复发性疾病向临床医生提供建议。根据我们的研究，磁共振成像似乎是评估骶骨侵犯和转移以及区分纤维化肿块与复发性肿瘤的更好方式。
