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来自印度泰米尔纳德邦讲泰米尔语人群的2491份脐带血样本的人类白细胞抗原(HLA)-A、-B、-C、-DRB1和-DQB1单倍型频率。

Human leucocyte antigen (HLA)-A, -B, -C, -DRB1 and -DQB1 haplotype frequencies from 2491 cord blood units from Tamil speaking population from Tamil Nadu, India.

作者信息

Narayan Saranya, Maiers Martin, Halagan Mike, Sathishkannan Arunadevi, Naganathan Chandramouleeswaran, Madbouly Abeer, Periathiruvadi Srinivasan

机构信息

Jeevan Stem Cell Foundation, No. 22, Wheatcrofts Road, Nungambakkam, Chennai, 600034, India.

National Marrow Donor Program, Minneapolis, MN, USA.

出版信息

Mol Biol Rep. 2018 Dec;45(6):2821-2829. doi: 10.1007/s11033-018-4382-6. Epub 2018 Sep 18.

Abstract

The Public Cord Blood Bank of Jeevan Stem Cell Foundation was established in 2008 to harvest cord blood units and make them available to treat multiple blood disorders through Hematopoietic Stem Cell Transplants. We studied Human Leucocyte Antigen (HLA)-A, -B, -C, -DRB1 and -DQB1 allele and haplotype diversity in a sample of 2491 unrelated cord-blood units from Jeevan's Public Cord Blood Bank (part of Be The Cure Registry) in the Tamil Nadu state in the Indian Peninsula.

摘要

吉万干细胞基金会公共脐带血库于2008年成立,旨在采集脐带血单位,并通过造血干细胞移植将其用于治疗多种血液疾病。我们研究了来自印度半岛泰米尔纳德邦吉万公共脐带血库(“成为治愈者登记处”的一部分)的2491份无关脐带血样本中的人类白细胞抗原(HLA)-A、-B、-C、-DRB1和-DQB1等位基因及单倍型多样性。

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